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- Title
STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis.
- Authors
Rodriguez, Moses; Zoecklein, Laurie; Gamez, Jeffrey D.; Pavelko, Kevin D.; Papke, Louisa M.; Nakane, Shunya; Howe, Charles; Radhakrishnan, Suresh; Hansen, Michael J.; David, Chella S.; Warrington, Arthur E.; Pease, Larry R.
- Abstract
Presents a study that investigated STAT4- and STAT6-signaling molecules in a murine model of multiple sclerosis. Development of spinal cord demyelinating lesions after virus infection in mice; Normal humoral immune responses of mice to TMEV infection; Effect of deletion of STAT4 or STAT6; Mechanism of the late demyelinating model of the late demyelinating phenotype.
- Subjects
MICE; MOLECULES; MULTIPLE sclerosis; CENTRAL nervous system; IMMUNE response; GENOTYPE-environment interaction; DEMYELINATION
- Publication
FASEB Journal, 2006, Vol 20, Issue 2, p343
- ISSN
0892-6638
- Publication type
Article
- DOI
10.1096/fj.05-4650fje