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- Title
The effects of vıtal dyes on mechanıcal propertıes of the human anterıor lens capsule.
- Authors
Simsek, Cem; Gokmen, Onur
- Abstract
<bold>Purpose: </bold>The purpose of this study was to evaluate the mechanical effects of vital dyes on the anterior lens capsule via the nanoindentation method.<bold>Methods: </bold>Twenty anterior lens capsules of 20 different patients were dissected into four equal fragments. Each fragment was stained separately with dyes for intraocular surgeries, such as trypan blue 0.06% (TB), brilliant blue 0.025% (BB), and indocyanine green 0.05% (ICG), for 1 min. The remaining fragment was assessed as an untreated control group. The alterations on the mechanical characteristics of the anterior lens capsule were evaluated using a nanoindentation testing device with Oliver-Pharr and Martens hardness methods.<bold>Results: </bold>The mean values of elasticity were 7.842 ± 0.55 GPa for capsules fragments stained with TB (P < 0.05), 8.407 ± 0.82 GPa for capsules fragments stained with BB (P < 0.05), 8.557 ± 0.60 GPa for ICG (P < 0.05), and 6.09 ± 0.57 GPa for the untreated control group. The mean values of stiffness were 299.7 ± 47 MPa for TB (P < 0.05), 317.9 ± 34 MPa for BB (P < 0.05), 331.8 ± 48 MPa for ICG (P < 0.05), and 229.85 ± 44 MPa for the untreated control group. The elasticity of the capsules statistically decreased in comparison to the control group, and the capsule stiffness showed a statistically significant increase in comparison to the untreated controls.<bold>Conclusion: </bold>The mechanical characteristics of the human anterior lens capsule were affected in association with the alterations in the elasticity and stiffness properties of the capsule as a result of exposure to three different dyes.
- Subjects
NANOINDENTATION tests; TRYPAN blue; INDOCYANINE green; DYES &; dyeing; LENSES
- Publication
Indian Journal of Ophthalmology, 2020, Vol 68, Issue 1, p66
- ISSN
0301-4738
- Publication type
journal article
- DOI
10.4103/ijo.IJO_285_19