We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Perkutane renale Denervierung bei therapieresistenter Hypertonie - Erste Erfahrungen in Österreich.
- Authors
Goliasch, Georg; Wolzt, Michael; Höfer, Peter; Delle-Karth, Georg; Kreiner, Gerhard; Neunteufel, Thomas; Maurer, Gerald; Binder, Thomas
- Abstract
BACKGROUND: Hypertension is a major public health issue. Many patients do not reach the target blood pressure despite antihypertensive combination therapy. Renal ablation is a new therapeutic approach for patients who are refractory. Using a percutaneous catheter-based approach the sympathetic nervous system is interrupted by radiofrequency ablation via both renal arteries. METHODS AND RESULTS: We describe the first renal denervation in Austria in a patient included in the "SIMPLICITY HTN-2" trial with resistant hypertension. We report of a 59-year-old patient in whom adequate blood-pressure control could not be achieved despite antihypertensive combination therapy with 6 different drugs. The averaged baseline blood-pressure was 238/132. Three months after renal denervation blood pressure dropped to 154/87 and medication was reduced on patient's request to 4 drugs. At 6-month follow-up 24h ambulatory blood-pressure monitoring was performed with an average value of 132/81. No adverse alterations of renal function could be detected. DISCUSSION: This case report is in line with studies, which show that renal denervation of the sympathetic nervous system is a promising and safe therapeutic option in patients with resistant hypertension. Nevertheless prospective randomized controlled trials will have to confirm the therapeutic effects and further implications of this new therapeutic modality.
- Subjects
DENERVATION; HYPERTENSION; CARDIOVASCULAR diseases; ANTIHYPERTENSIVE agents; RENAL artery
- Publication
Wiener Klinische Wochenschrift, 2010, Vol 122, Issue 23/24, p723
- ISSN
0043-5325
- Publication type
Article
- DOI
10.1007/s00508-010-1486-y