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- Title
Epidemiology of male osteoporosis in Denmark (1996–2018).
- Authors
Bruhn, Rasmus; Pedersen, Alma Becic; Heide-Jørgensen, Uffe; Ehrenstein, Vera
- Abstract
Summary: Osteoporosis in men may be underdiagnosed. One in four men in Denmark will develop osteoporosis after age of 50 years, with fracture as a common presenting symptom. Purpose: The aim of this study was to describe epidemiology of male osteoporosis in Denmark. Methods: In this nationwide registry-based cohort study, we identified men with osteoporosis, 50 years or older, residing in Denmark, during the years 1996–2018. Osteoporosis was defined as one of the following: a hospital diagnosis of osteoporosis; a hospital diagnosis of osteoporosis fracture; or an outpatient dispensing of an anti-osteoporosis medication. We reported annual incidence and prevalence and described the distribution of fractures, comorbidities, socioeconomic status, and initiation of anti-osteoporosis therapy among men with osteoporosis. Selected characteristics were also described among men without osteoporosis of similar age. Results: There were 171,186 men fulfilling the study criteria for osteoporosis. The overall age-standardized incidence rate of osteoporosis was 8.6 per 1000 person-years (95% confidence interval (CI), 8.5–8.6), varying between 7.7 and 9.7, while the prevalence increased from 4.3% (95% CI, 4.2–4.3) to 7.1% (95% CI, 7.0–7.1) during the 22-year period. The remaining-lifetime risk of developing osteoporosis after age of 50 years was close to 30%. The proportion of men initiating anti-osteoporosis treatment within 1 year of diagnosis increased from 6.9% to 29.8%. Men with osteoporosis had more comorbidities and redeemed more medication than did men without osteoporosis of similar age. Conclusion: Osteoporosis among men may be undertreated despite increasing treatment initiation.
- Subjects
DENMARK; OSTEOPOROSIS diagnosis; DIAGNOSIS of bone fractures; BONE fracture prevention; OSTEOPOROSIS prevention; REPORTING of diseases; MEN'S health; CONFIDENCE intervals; AGE distribution; DISEASE incidence; OSTEOPOROSIS; SOCIOECONOMIC factors; RISK assessment; RESEARCH funding; DESCRIPTIVE statistics; DATA analysis software; BONE fractures; LONGITUDINAL method; COMORBIDITY
- Publication
Osteoporosis International, 2023, Vol 34, Issue 5, p935
- ISSN
0937-941X
- Publication type
Article
- DOI
10.1007/s00198-023-06720-y