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- Title
Waterpipe smoking: the role of humectants in the release of toxic carbonyls.
- Authors
Schubert, Jens; Heinke, Volkmar; Bewersdorff, Jana; Luch, Andreas; Schulz, Thomas
- Abstract
In recent years, the number of waterpipe smokers has increased substantially worldwide. Here, we present a study on the identification and quantification of seven carbonylic compounds including formaldehyde, acetaldehyde and acrolein in the mainstream smoke of the waterpipe. Smoking was conducted with a smoking machine, and carbonyls were scavenged from the smoke with two impingers containing an acidic solution of 2,4-dinitrophenylhydrazine. The derivatives were then analyzed by high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS). For instance, during one waterpipe smoking session, up to 111 ± 12 μg formaldehyde could be detected. This value is about 5 times higher when compared to one 2R4F reference cigarette. We also found a distinct filter effect of the bowl water for all carbonyls investigated. Our data further demonstrate that increasing amounts of humectants in the unburned tobacco lowers the temperature in the waterpipe head during smoking, thereby resulting in decreasing levels of carbonyls in the smoke produced. Altogether, considerable amounts of toxic carbonyls are present in the waterpipe smoke, thus conferring a health risk to waterpipe smokers.
- Subjects
HOOKAHS; HUMECTANTS; CARBONYL compounds; FORMALDEHYDE; ACETALDEHYDE; ACROLEIN; HIGH performance liquid chromatography; TANDEM mass spectrometry
- Publication
Archives of Toxicology, 2012, Vol 86, Issue 8, p1309
- ISSN
0340-5761
- Publication type
Article
- DOI
10.1007/s00204-012-0884-5