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- Title
Comparison of Clinical Features and Treatment Results of Mix Mucinous Carcinomas and Other Atypical Carcinomas of the Breast.
- Authors
Gök, Mustafa; Topal, Uğur; Öz, Abdullah Bahadır; Akgün, Hülya; Akcan, Alper Celal; Sözüer, Erdoğan Mütevelli
- Abstract
Objective: There are multiple subtypes of breast cancer with different biological and pathological features and accordingly exhibit different clinical behaviors. Mucinous breast carcinoma (MBC) carcinoma represents approximately 1-6% of all malignant breast carcinoma and is divided into pure (PMBC) and mix (MMBC) subtypes. The aim of this study was to compare the treatment modalities, clinical features and prognostic characteristics of Mix Mucinous Carcinomas (MMBC) and other rare tumors of the breast. Materials and Methods: A total of 2152 patients who were operated on for breast cancer in our clinic between 2010-2019, with pathological diagnoses of tubular, pure mucinous, mix mucinous or papillary carcinoma were enrolled in the study. Patients were divided into two groups as mix mucinous patients (Group 1) and other rare tumors (Group 2). The demographic, clinical and prognostic characteristics and treatment approaches were compared between Groups, and additionally between the subtypes of Group 2. Results: 42 patients participated in our study. Group 1 consisted of 7 patients, and Group2 consisted of 35 patients. The subtypes in Group2 were papillary (n=21), pure mucinous (n=10) and tubular (n=4). Progesterone Receptor Positivity was found to be significantly higher in Group 2 patients than in Group 1 patients (p=0.005, p<0.05). Multicentricity rates in the tumors of the patients in Group1 were found to be statistically significantly higher than the patients in Group 2 (p=0.024, p<0.05). In subtype analysis in Group2, there were no statistically significant differences parameters in the subgroups (p>0.05). Mean survival was was 19.5+5.6 (8.5-30.5) months in Group 1 and 46.3+5.2 (36.1-56.6) months, in Group2 when evaluated separately (p: 0.002). Conclusion: Atypical tumors of the breast are seen at a rate of 2% in our series. The prognosis of pure mucinosis (PMBC) and other atypical cancers of the breast compared to the (MMBC) is quite good.
- Subjects
BREAST cancer treatment; BREAST cancer diagnosis; BREAST tumors; BREAST cancer prognosis; PAPILLARY carcinoma
- Publication
European Journal of Breast Health, 2019, Vol 15, pS13
- ISSN
2587-0831
- Publication type
Article