We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Inodilators May Improve the In-Hospital Mortality of Patients with Cardiogenic Shock Undergoing Veno-Arterial Extracorporeal Membrane Oxygenation.
- Authors
Kim, Mijoo; Seong, Seok-Woo; Song, Pil Sang; Jeong, Jin-Ok; Yang, Jeong Hoon; Gwon, Hyeon-Cheol; Ko, Young-Guk; Yu, Cheol Woong; Chun, Woo Jung; Jang, Woo Jin; Kim, Hyun-Joong; Bae, Jang-Whan; Kwon, Sung Uk; Lee, Hyun-Jong; Lee, Wang Soo; Park, Sang-Don; Cho, Sung Soo; Park, Jae-Hyeong
- Abstract
Although inodilators (dobutamine and milrinone) are widely used empirically for cardiogenic shock (CS), the efficacy of inodilators for patients with CS undergoing veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is controversial. We evaluated the effects of inodilators on clinical outcomes using the RESCUE (REtrospective and prospective observational Study to investigate Clinical oUtcomes and Efficacy of left ventricular assist device for Korean patients with cardiogenic shock; NCT02985008) registry. We selected and analyzed the clinical outcomes of 496 patients who underwent VA-ECMO and did or did not receive inodilators. Of the 496 patients, 257 (51.8%) died during hospitalization. We selected 191 matched pairs to adjust for baseline clinical characteristics after 1:1 propensity score matching (PSM). The univariate and multivariate analyses showed that the inodilator group had significantly lower in-hospital mortality than the no-inodilator group (unadjusted hazard ratio [HR], 0.768; 95% confidence interval [CI], 0.579–1.018; p = 0.066, adjusted HR, 0.702; 95% CI, 0.552–0.944; p = 0.019). For patients with CS undergoing VA-ECMO, inodilators may improve clinical outcomes.
- Subjects
EXTRACORPOREAL membrane oxygenation; CARDIOGENIC shock; HOSPITAL mortality; HEART assist devices; PROPENSITY score matching; KOREANS
- Publication
Journal of Clinical Medicine, 2022, Vol 11, Issue 17, p4958
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm11174958