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- Title
Evolving Microbiology and Treatment of Extracavitary Prosthetic Graft Infections.
- Authors
Stone, Patrick A.; Back, Martin R.; Armstrong, Paul A.; Brumberg, Robert S.; Flaherty, Sarah K.; Johnson, Brad L.; Shames, Murray L.; Bandyk, Dennis F.
- Abstract
The authors report the microbiology and outcomes following an individualized treatment algorithm for extracavitary (EC) prosthetic graft infection, including the use of graft preservation and in situ graft replacement techniques. A retrospective 8-year review of 87 patients treated for EC prosthetic graft infections was carried out. The treatment algorithm included culture-specific antibiotic therapy, surgical site debridement with antibiotic bead placement, selected graft preservation with muscle flap coverage, or graft excision with in situ conduit replacement. Outcomes measured included death, limb loss, and recurrent infection. It was found that present-day management of EC prosthetic graft infections is associated with lower mortality and morbidity despite changes in microbiology and the increased application of graft preservation and in situ grafting treatments.
- Subjects
MICROBIOLOGY; PROSTHETICS; OPERATIVE surgery; ALGORITHMS; MEDICAL research
- Publication
Vascular & Endovascular Surgery, 2008, Vol 42, Issue 6, p537
- ISSN
1538-5744
- Publication type
Article
- DOI
10.1177/1538574408322658