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- Title
Endurance training-induced cardiac remodeling in a guinea pig athlete's heart model.
- Authors
Topal, L.; Polyák, A.; Tóth, N.; Ágoston, G.; Bencsik, P.; Kohajda, Zs.; Prorok, J.; Déri, Sz.; Nagy, N.; Jost, N.; Virág, L.; Farkas, A.S.; Varró, A.; Baczkó, I.
- Abstract
The article reviews the study to investigate the effects of long-term vigorous training and its potentially detrimental structural-functional changes in a male guinea pigs athlete's heart model. The exercised animals exhibited structural left ventricular enlargement and a significantly higher degree of myocardial fibrosis. The detected structural-functional changes share similarities with the human athlete's heart making the model useful for investigations on cardiac remodeling.
- Publication
Canadian Journal of Physiology & Pharmacology, 2022, Vol 100, Issue 10, p993
- ISSN
0008-4212
- Publication type
Article
- DOI
10.1139/cjpp-2022-0073