We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
An Electrochemical Sensor for Fentanyl Detection Based on Multi-Walled Carbon Nanotubes as Electrocatalyst and the Electrooxidation Mechanism.
- Authors
Mostafa Najafi; Sohouli, Esmail; Mousavi, Farimah
- Abstract
The electrochemical behavior and determination of fentanyl as a strong analgesic drug was studied at the surface of glassy carbon electrode (GCE) modified by multi-walled carbon nanotubes (MWCNTs). The electrochemical determination of fentanyl was accomplished by differential pulse adsorptive stripping voltammetry after preconcentration under open circuit potential. The distribution of adsorbed MWCNTs on the surface of GCE was studied by scanning electron microscopy. Experimental parameters such as pH and accumulation conditions were optimized by monitoring the cyclic voltammetry responses toward fentanyl oxidation. Under the optimized conditions, the modified electrode showed a wide linear dynamic range from 5 × 10–7 to 1 × 10–4 M with a detection limit of 1 × 10–7 M for the voltammetric determination of fentanyl. Also, a probable mechanism for the electrooxidation of fentanyl was proposed. The prepared electrode was successfully applied to the determination of fentanyl in presence of interferents and also in real samples such as pharmaceutical preparation, human serum and urine.
- Subjects
ELECTROCHEMICAL sensors; CARBON nanotubes; SINGLE walled carbon nanotubes; FENTANYL; CARBON electrodes; CYCLIC voltammetry; SCANNING electron microscopy
- Publication
Journal of Analytical Chemistry, 2020, Vol 75, Issue 9, p1209
- ISSN
1061-9348
- Publication type
Article
- DOI
10.1134/S1061934820090130