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- Title
Hepatocellular Carcinoma: Optimal Radiological Evaluation before Liver Transplantation.
- Authors
Dioguardi Burgio, Marco; Garzelli, Lorenzo; Cannella, Roberto; Ronot, Maxime; Vilgrain, Valérie
- Abstract
Liver transplantation (LT) is the recommended curative-intent treatment for patients with early or intermediate-stage hepatocellular carcinoma (HCC) who are ineligible for resection. Imaging plays a central role in staging and for selecting the best LT candidates. This review will discuss recent developments in pre-LT imaging assessment, in particular LT eligibility criteria on imaging, the technical requirements and the diagnostic performance of imaging for the pre-LT diagnosis of HCC including the recent Liver Imaging Reporting and Data System (LI-RADS) criteria, the evaluation of the response to locoregional therapy, as well as the non-invasive prediction of HCC aggressiveness and its impact on the outcome of LT. We will also briefly discuss the role of nuclear medicine in the pre-LT evaluation and the emerging role of artificial intelligence models in patients with HCC.
- Subjects
LIVER transplantation; HEPATOCELLULAR carcinoma; NUCLEAR medicine; ARTIFICIAL intelligence; DIAGNOSTIC imaging
- Publication
Life (2075-1729), 2023, Vol 13, Issue 12, p2267
- ISSN
2075-1729
- Publication type
Article
- DOI
10.3390/life13122267