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- Title
The efficacy of botanical drugs in orchestrating epigenetic modifications for ameliorating metabolic disorders.
- Authors
Ariyanto, Eko Fuji
- Abstract
This article discusses the potential of botanical drugs in treating metabolic disorders through epigenetic modifications. It highlights the role of DNA methylation, histone modifications, and non-coding RNA regulation in the development of metabolic diseases. Botanical drugs derived from plants have shown promise in improving metabolic conditions by modulating these epigenetic pathways. However, further research is needed to fully understand their effectiveness and ensure their safety. The article emphasizes the importance of comprehensive toxicity studies and evaluating potential drug interactions. Overall, botanical drugs have potential in treating metabolic diseases, but more research is needed to fully understand their mechanisms and ensure their safe use. Additionally, the document provides a list of references for scientific studies exploring the effects of natural compounds on epigenetic modifications in various health conditions. These studies focus on compounds like esculetin, curcumin, anacardic acid, kaempferol, and quercetin, and their potential therapeutic applications in managing conditions such as type 2 diabetes, cardiomyopathy, obesity, atherosclerosis, and hypertension.
- Subjects
MEDICAL botany; EPIGENOMICS; EPIGENETICS; METABOLIC disorders; DRUG efficacy; MEDICAL sciences; WEIGHT gain; BERBERINE; LYCOPENE
- Publication
Frontiers in Pharmacology, 2024, p1
- ISSN
1663-9812
- Publication type
Article
- DOI
10.3389/fphar.2024.1366551