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Insights into the genetic architecture of haematological traits from deep phenotyping and whole-genome sequencing for two Mediterranean isolated populations.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-021-04436-9
By:
- Kuchenbaecker, Karoline;
- Gilly, Arthur;
- Suveges, Daniel;
- Southam, Lorraine;
- Giannakopoulou, Olga;
- Kilian, Britt;
- Tsafantakis, Emmanouil;
- Karaleftheri, Maria;
- Farmaki, Aliki-Eleni;
- Gurdasani, Deepti;
- Kundu, Kousik;
- Sandhu, Manjinder S.;
- Danesh, John;
- Butterworth, Adam;
- Barroso, Inês;
- Dedoussis, George;
- Zeggini, Eleftheria
Publication type:
Article
Genetically personalised organ-specific metabolic models in health and disease.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35017-7
By:
- Foguet, Carles;
- Xu, Yu;
- Ritchie, Scott C.;
- Lambert, Samuel A.;
- Persyn, Elodie;
- Nath, Artika P.;
- Davenport, Emma E.;
- Roberts, David J.;
- Paul, Dirk S.;
- Di Angelantonio, Emanuele;
- Danesh, John;
- Butterworth, Adam S.;
- Yau, Christopher;
- Inouye, Michael
Publication type:
Article
Systematic Mendelian randomization using the human plasma proteome to discover potential therapeutic targets for stroke.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33675-1
By:
- Chen, Lingyan;
- Peters, James E.;
- Prins, Bram;
- Persyn, Elodie;
- Traylor, Matthew;
- Surendran, Praveen;
- Karthikeyan, Savita;
- Yonova-Doing, Ekaterina;
- Di Angelantonio, Emanuele;
- Roberts, David J.;
- Watkins, Nicholas A.;
- Ouwehand, Willem H.;
- Danesh, John;
- Lewis, Cathryn M.;
- Bronson, Paola G.;
- Markus, Hugh S.;
- Burgess, Stephen;
- Butterworth, Adam S.;
- Howson, Joanna M. M.
Publication type:
Article
The influence of rare variants in circulating metabolic biomarkers.
Published in:
PLoS Genetics, 2020, v. 16, n. 3, p. 1, doi. 10.1371/journal.pgen.1008605
By:
- Riveros-Mckay, Fernando;
- Oliver-Williams, Clare;
- Karthikeyan, Savita;
- Walter, Klaudia;
- Kundu, Kousik;
- Ouwehand, Willem H.;
- Roberts, David;
- Di Angelantonio, Emanuele;
- Soranzo, Nicole;
- Danesh, John;
- Wheeler, Eleanor;
- Zeggini, Eleftheria;
- Butterworth, Adam S.;
- Barroso, Inês
Publication type:
Article
Lifestyle factors and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study.
Published in:
2020
By:
- Freisling, Heinz;
- Viallon, Vivian;
- Lennon, Hannah;
- Bagnardi, Vincenzo;
- Ricci, Cristian;
- Butterworth, Adam S.;
- Sweeting, Michael;
- Muller, David;
- Romieu, Isabelle;
- Bazelle, Pauline;
- Kvaskoff, Marina;
- Arveux, Patrick;
- Severi, Gianluca;
- Bamia, Christina;
- Kühn, Tilman;
- Kaaks, Rudolf;
- Bergmann, Manuela;
- Boeing, Heiner;
- Tjønneland, Anne;
- Olsen, Anja
Publication type:
journal article
Flashfm-ivis: interactive visualization for fine-mapping of multiple quantitative traits.
Published in:
Bioinformatics, 2022, v. 38, n. 17, p. 4238, doi. 10.1093/bioinformatics/btac453
By:
- Zhou, Feng;
- Butterworth, Adam S;
- Asimit, Jennifer L
Publication type:
Article
Leucocyte Telomere Length and Risk of Type 2 Diabetes Mellitus: New Prospective Cohort Study and Literature-Based Meta-Analysis.
Published in:
PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112483
By:
- Willeit, Peter;
- Raschenberger, Julia;
- Heydon, Emma E.;
- Tsimikas, Sotirios;
- Haun, Margot;
- Mayr, Agnes;
- Weger, Siegfried;
- Witztum, Joseph L.;
- Butterworth, Adam S.;
- Willeit, Johann;
- Kronenberg, Florian;
- Kiechl, Stefan
Publication type:
Article
Mendelian randomization for cardiovascular diseases: principles and applications.
Published in:
European Heart Journal, 2023, v. 44, n. 47, p. 4913, doi. 10.1093/eurheartj/ehad736
By:
- Larsson, Susanna C;
- Butterworth, Adam S;
- Burgess, Stephen
Publication type:
Article
Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis.
Published in:
European Heart Journal, 2021, v. 42, n. 12, p. 1160, doi. 10.1093/eurheartj/ehaa972
By:
- Wang, Qin;
- Oliver-Williams, Clare;
- Raitakari, Olli T;
- Viikari, Jorma;
- Lehtimäki, Terho;
- Kähönen, Mika;
- Järvelin, Marjo-Riitta;
- Salomaa, Veikko;
- Perola, Markus;
- Danesh, John;
- Kettunen, Johannes;
- Butterworth, Adam S;
- Holmes, Michael V;
- Ala-Korpela, Mika
Publication type:
Article
Integrated analyses of growth differentiation factor-15 concentration and cardiometabolic diseases in humans.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.76272
By:
- Lemmelä, Susanna;
- Wigmore, Eleanor M.;
- Benner, Christian;
- Havulinna, Aki S.;
- Ong, Rachel M. Y.;
- Kempf, Tibor;
- Wollert, Kai C.;
- Blankenberg, Stefan;
- Zeller, Tanja;
- Peters, James E.;
- Salomaa, Veikko;
- Fritsch, Maria;
- March, Ruth;
- Palotie, Aarno;
- Daly, Mark;
- Butterworth, Adam S.;
- Kinnunen, Mervi;
- Paul, Dirk S.;
- Matakidou, Athena
Publication type:
Article
Genome-wide analysis identifies molecular systems and 149 genetic loci associated with income.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-13585-5
By:
- Hill, W. David;
- Davies, Neil M.;
- Ritchie, Stuart J.;
- Skene, Nathan G.;
- Bryois, Julien;
- Bell, Steven;
- Di Angelantonio, Emanuele;
- Roberts, David J.;
- Xueyi, Shen;
- Davies, Gail;
- Liewald, David C. M.;
- Porteous, David J.;
- Hayward, Caroline;
- Butterworth, Adam S.;
- McIntosh, Andrew M.;
- Gale, Catharine R.;
- Deary, Ian J.
Publication type:
Article
Author Correction: Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07730-9
By:
- Gilly, Arthur;
- Suveges, Daniel;
- Kuchenbaecker, Karoline;
- Pollard, Martin;
- Southam, Lorraine;
- Hatzikotoulas, Konstantinos;
- Farmaki, Aliki-Eleni;
- Bjornland, Thea;
- Waples, Ryan;
- Appel, Emil V. R.;
- Casalone, Elisabetta;
- Melloni, Giorgio;
- Kilian, Britt;
- Rayner, Nigel W.;
- Ntalla, Ioanna;
- Kundu, Kousik;
- Walter, Klaudia;
- Danesh, John;
- Butterworth, Adam;
- Barroso, Inês
Publication type:
Article
Cohort-wide deep whole genome sequencing and the allelic architecture of complex traits.
Published in:
Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07070-8
By:
- Gilly, Arthur;
- Suveges, Daniel;
- Kuchenbaecker, Karoline;
- Pollard, Martin;
- Southam, Lorraine;
- Hatzikotoulas, Konstantinos;
- Farmaki, Aliki-Eleni;
- Bjornland, Thea;
- Waples, Ryan;
- Appel, Emil V. R.;
- Casalone, Elisabetta;
- Melloni, Giorgio;
- Kilian, Britt;
- Rayner, Nigel W.;
- Ntalla, Ioanna;
- Kundu, Kousik;
- Walter, Klaudia;
- Danesh, John;
- Butterworth, Adam;
- Barroso, Inês
Publication type:
Article
Large genome-wide association study identifies three novel risk variants for restless legs syndrome.
Published in:
Communications Biology, 2020, v. 3, n. 1, p. N.PAG, doi. 10.1038/s42003-020-01430-1
By:
- Didriksen, Maria;
- Nawaz, Muhammad Sulaman;
- Dowsett, Joseph;
- Bell, Steven;
- Erikstrup, Christian;
- Pedersen, Ole B.;
- Sørensen, Erik;
- Jennum, Poul J.;
- Burgdorf, Kristoffer S.;
- Burchell, Brendan;
- Butterworth, Adam S.;
- Soranzo, Nicole;
- Rye, David B.;
- Trotti, Lynn Marie;
- Saini, Prabhjyot;
- Stefansdottir, Lilja;
- Magnusson, Sigurdur H.;
- Thorleifsson, Gudmar;
- Sigmundsson, Thordur;
- Sigurdsson, Albert P.
Publication type:
Article
Trans‐ethnic polygenic risk scores for body mass index: An international hundred K+ cohorts consortium study.
Published in:
Clinical & Translational Medicine, 2023, v. 13, n. 6, p. 1, doi. 10.1002/ctm2.1291
By:
- Qu, Hui‐Qi;
- Connolly, John J;
- Kraft, Peter;
- Long, Jirong;
- Pereira, Alexandre;
- Flatley, Christopher;
- Turman, Constance;
- Prins, Bram;
- Mentch, Frank;
- Lotufo, Paulo A;
- Magnus, Per;
- Stampfer, Meir J;
- Tamimi, Rulla;
- Eliassen, A Heather;
- Zheng, Wei;
- Knudsen, Gun Peggy Stromstad;
- Helgeland, Oyvind;
- Butterworth, Adam S.;
- Hakonarson, Hakon;
- Sleiman, Patrick M.
Publication type:
Article
The blood metabolome of incident kidney cancer: A case-control study nested within the MetKid consortium.
Published in:
2021
By:
- Guida, Florence;
- Tan, Vanessa Y.;
- Corbin, Laura J.;
- Smith-Byrne, Karl;
- Alcala, Karine;
- Langenberg, Claudia;
- Stewart, Isobel D.;
- Butterworth, Adam S.;
- Surendran, Praveen;
- Achaintre, David;
- Adamski, Jerzy;
- Amiano Exezarreta, Pilar;
- Bergmann, Manuela M.;
- Bull, Caroline J.;
- Dahm, Christina C.;
- Gicquiau, Audrey;
- Giles, Graham G.;
- Gunter, Marc J.;
- Haller, Toomas;
- Langhammer, Arnulf
Publication type:
journal article
Genetically predicted plasma cortisol and common chronic diseases: A Mendelian randomization study.
Published in:
Clinical Endocrinology, 2024, v. 100, n. 3, p. 238, doi. 10.1111/cen.14966
By:
- Lee, Wei‐Hsuan;
- Larsson, Susanna C.;
- Wood, Angela;
- Di Angelantonio, Emanuele;
- Butterworth, Adam S.;
- Burgess, Stephen;
- Allara, Elias
Publication type:
Article
Identification of blood protein biomarkers associated with prostate cancer risk using genetic prediction models: analysis of over 140,000 subjects.
Published in:
Human Molecular Genetics, 2023, v. 32, n. 22, p. 3181, doi. 10.1093/hmg/ddad139
By:
- Zhong, Hua;
- Zhu, Jingjing;
- Liu, Shuai;
- Ghoneim, Dalia H;
- Surendran, Praveen;
- Liu, Tao;
- Fahle, Sarah;
- Butterworth, Adam;
- Alam, Md Ashad;
- Deng, Hong-Wen;
- Yu, Herbert;
- Wu, Chong;
- Wu, Lang
Publication type:
Article
Risk factors and prediction models for incident heart failure with reduced and preserved ejection fraction.
Published in:
ESC Heart Failure, 2021, v. 8, n. 6, p. 4893, doi. 10.1002/ehf2.13429
By:
- Gaziano, Liam;
- Cho, Kelly;
- Djousse, Luc;
- Schubert, Petra;
- Galloway, Ashley;
- Ho, Yuk‐Lam;
- Kurgansky, Katherine;
- Gagnon, David R.;
- Russo, John P.;
- Di Angelantonio, Emanuele;
- Wood, Angela M.;
- Danesh, John;
- Gaziano, John Michael;
- Butterworth, Adam S.;
- Wilson, Peter W.F.;
- Joseph, Jacob
Publication type:
Article
Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: a systematic review and meta-analysis with evidence from up to 331 175 individuals.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 12, p. 3582, doi. 10.1093/hmg/ddv097
By:
- Nead, Kevin T.;
- Aihua Li;
- Wehner, Mackenzie R.;
- Neupane, Binod;
- Gustafsson, Stefan;
- Butterworth, Adam;
- Engert, James C.;
- Davis, A. Darlene;
- Hegele, Robert A.;
- Miller, Ruby;
- den Hoed, Marcel;
- Kay-Tee Khaw;
- Kilpeläinen, Tuomas O.;
- Wareham, Nick;
- Edwards, Todd L.;
- Hallmans, Göran;
- Varga, Tibor V.;
- Kardia, Sharon L. R.;
- Smith, Jennifer A.;
- Wei Zhao
Publication type:
Article
Association of Triglyceride-Lowering LPL Variants and LDL-C-Lowering LDLR Variants With Risk of Coronary Heart Disease.
Published in:
2019
By:
- Ference, Brian A.;
- Kastelein, John J. P.;
- Ray, Kausik K.;
- Ginsberg, Henry N.;
- Chapman, M. John;
- Packard, Chris J.;
- Laufs, Ulrich;
- Oliver-Williams, Clare;
- Wood, Angela M.;
- Butterworth, Adam S.;
- Di Angelantonio, Emanuele;
- Danesh, John;
- Nicholls, Stephen J.;
- Bhatt, Deepak L.;
- Sabatine, Marc S.;
- Catapano, Alberico L.
Publication type:
journal article
Association of Genetic Variants Related to CETP Inhibitors and Statins With Lipoprotein Levels and Cardiovascular Risk.
Published in:
2017
By:
- Ference, Brian A.;
- Kastelein, John J. P.;
- Ginsberg, Henry N.;
- Chapman, M. John;
- Nicholls, Stephen J.;
- Ray, Kausik K.;
- Packard, Chris J.;
- Laufs, Ulrich;
- Brook, Robert D.;
- Oliver-Williams, Clare;
- Butterworth, Adam S.;
- Danesh, John;
- Smith, George Davey;
- Catapano, Alberico L.;
- Sabatine, Marc S.
Publication type:
journal article
Development and evaluation of a transfusion medicine genome wide genotyping array.
Published in:
2019
By:
- Guo, Yuelong;
- Busch, Michael P.;
- Seielstad, Mark;
- Endres‐Dighe, Stacy;
- Westhoff, Connie M.;
- Keating, Brendan;
- Hoppe, Carolyn;
- Bordbar, Aarash;
- Custer, Brian;
- Butterworth, Adam S.;
- Kanias, Tamir;
- Mast, Alan E.;
- Kleinman, Steve;
- Lu, Yontao;
- Page, Grier P.;
- Endres-Dighe, Stacy;
- National Heart, Lung, and Blood Institute Recipient Epidemiology Donor Evaluation Study (REDS)-III
Publication type:
journal article
Development and evaluation of a transfusion medicine genome wide genotyping array.
Published in:
Transfusion, 2019, v. 59, n. 1, p. 101, doi. 10.1111/trf.15012
By:
- Guo, Yuelong;
- Busch, Michael P.;
- Seielstad, Mark;
- Endres‐Dighe, Stacy;
- Westhoff, Connie M.;
- Keating, Brendan;
- Hoppe, Carolyn;
- Bordbar, Aarash;
- Custer, Brian;
- Butterworth, Adam S.;
- Kanias, Tamir;
- Mast, Alan E.;
- Kleinman, Steve;
- Lu, Yontao;
- Page, Grier P.
Publication type:
Article
Genome-Wide Association Studies, Field Synopses, and the Development of the Knowledge Base on Genetic Variation and Human Diseases.
Published in:
American Journal of Epidemiology, 2009, v. 170, n. 3, p. 269, doi. 10.1093/aje/kwp119
By:
- Khoury, Muin J.;
- Bertram, Lars;
- Boffetta, Paolo;
- Butterworth, Adam S.;
- Chanock, Stephen J.;
- Dolan, Siobhan M.;
- Fortier, Isabel;
- Garcia-Closas, Montserrat;
- Gwinn, Marta;
- Higgins, Julian P. T.;
- Janssens, A. Cecile J. W.;
- Ostell, James;
- Owen, Ryan P.;
- Pagon, Roberta A.;
- Rebbeck, Timothy R.;
- Rothman, Nathaniel;
- Bernstein, Jonine L.;
- Burton, Paul R.;
- Campbell, Harry;
- Chockalingam, Anand
Publication type:
Article
Seven Lipoprotein Lipase Gene Polymorphisms, Lipid Fractions, and Coronary Disease: A HuGE Association Review and Meta-Analysis.
Published in:
American Journal of Epidemiology, 2008, v. 168, n. 11, p. 1233, doi. 10.1093/aje/kwn235
By:
- Gurdeep S. Sagoo;
- Iain Tatt;
- Georgia Salanti;
- Adam S. Butterworth;
- Nadeem Sarwar;
- Merel van Maarle;
- J. Wouter Jukema;
- Björn Wiman;
- John J. P. Kastelein;
- Anna M. Bennet;
- Ulf de Faire;
- John Danesh;
- Julian P. T. Higgins
Publication type:
Article
Turning the Pump Handle: Evolving Methods for Integrating the Evidence on Gene-Disease Association.
Published in:
American Journal of Epidemiology, 2007, v. 166, n. 8, p. 863, doi. 10.1093/aje/kwm248
By:
- Julian P. T. Higgins;
- Julian Little;
- John P. A. Ioannidis;
- Molly S. Bray;
- Teri A. Manolio;
- Liam Smeeth;
- Jonathan A. Sterne;
- Betsy Anagnostelis;
- Adam S. Butterworth;
- John Danesh;
- Carol Dezateux;
- John E. Gallacher;
- Marta Gwinn;
- Sarah J. Lewis;
- Cosetta Minelli;
- Paul D. Pharoah;
- Georgia Salanti;
- Simon Sanderson;
- Lesley A. Smith;
- Emanuela Taioli
Publication type:
Article
Polygenic risk scores in cardiovascular risk prediction: A cohort study and modelling analyses.
Published in:
2021
By:
- Sun, Luanluan;
- Pennells, Lisa;
- Kaptoge, Stephen;
- Nelson, Christopher P.;
- Ritchie, Scott C.;
- Abraham, Gad;
- Arnold, Matthew;
- Bell, Steven;
- Bolton, Thomas;
- Burgess, Stephen;
- Dudbridge, Frank;
- Guo, Qi;
- Sofianopoulou, Eleni;
- Stevens, David;
- Thompson, John R.;
- Butterworth, Adam S.;
- Wood, Angela;
- Danesh, John;
- Samani, Nilesh J.;
- Inouye, Michael
Publication type:
journal article
ProGeM: a framework for the prioritization of candidate causal genes at molecular quantitative trait loci.
Published in:
Nucleic Acids Research, 2019, v. 47, n. 1, p. e3, doi. 10.1093/nar/gky837
By:
- Stacey, David;
- Fauman, Eric B;
- Ziemek, Daniel;
- Sun, Benjamin B;
- Harshfield, Eric L;
- Wood, Angela M;
- Butterworth, Adam S;
- Suhre, Karsten;
- Paul, Dirk S
Publication type:
Article
Associations between genetically predicted plasma protein levels and Alzheimer's disease risk: a study using genetic prediction models.
Published in:
Alzheimer's Research & Therapy, 2024, v. 16, p. 1, doi. 10.1186/s13195-023-01378-4
By:
- Zhu, Jingjing;
- Liu, Shuai;
- Walker, Keenan A.;
- Zhong, Hua;
- Ghoneim, Dalia H.;
- Zhang, Zichen;
- Surendran, Praveen;
- Fahle, Sarah;
- Butterworth, Adam;
- Alam, Md Ashad;
- Deng, Hong-Wen;
- Wu, Chong;
- Wu, Lang
Publication type:
Article
The common IL1A single nucleotide polymorphism rs17561 is a hypomorphic mutation that significantly reduces interleukin‐1α release from human blood cells.
Published in:
Immunology, 2023, v. 168, n. 3, p. 459, doi. 10.1111/imm.13584
By:
- Wiggins, Kimberley A.;
- Pyrillou, Katerina;
- Humphry, Melanie;
- Butterworth, Adam S.;
- Clarke, Murray CH.
Publication type:
Article
Information and Risk Modification Trial (INFORM): design of a randomised controlled trial of communicating different types of information about coronary heart disease risk, alongside lifestyle advice, to achieve change in health-related behaviour.
Published in:
BMC Public Health, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12889-015-2192-5
By:
- Silarova, Barbora;
- Lucas, Joanne;
- Butterworth, Adam S.;
- Di Angelantonio, Emanuele;
- Girling, Christine;
- Lawrence, Kathryn;
- Mackintosh, Stuart;
- Moore, Carmel;
- Payne, Rupert A.;
- Sharp, Stephen J.;
- Shefer, Guy;
- Tolkien, Zoe;
- Usher-Smith, Juliet;
- Walker, Matthew;
- Danesh, John;
- Griffin, Simon
Publication type:
Article
Information and Risk Modification Trial (INFORM): design of a randomised controlled trial of communicating different types of information about coronary heart disease risk, alongside lifestyle advice, to achieve change in health-related behaviour.
Published in:
BMC Public Health, 2015, v. 15, n. 1, p. 868, doi. 10.1186/s12889-015-2192-5
By:
- Silarova, Barbora;
- Lucas, Joanne;
- Butterworth, Adam S.;
- Di Angelantonio, Emanuele;
- Girling, Christine;
- Lawrence, Kathryn;
- Mackintosh, Stuart;
- Moore, Carmel;
- Payne, Rupert A.;
- Sharp, Stephen J.;
- Shefer, Guy;
- Tolkien, Zoe;
- Usher-Smith, Juliet;
- Walker, Matthew;
- Danesh, John;
- Griffin, Simon
Publication type:
Article
Information and Risk Modification Trial (INFORM): design of a randomised controlled trial of communicating different types of information about coronary heart disease risk, alongside lifestyle advice, to achieve change in health-related behaviour.
Published in:
2015
By:
- Silarova, Barbora;
- Lucas, Joanne;
- Butterworth, Adam S;
- Di Angelantonio, Emanuele;
- Girling, Christine;
- Lawrence, Kathryn;
- Mackintosh, Stuart;
- Moore, Carmel;
- Payne, Rupert A;
- Sharp, Stephen J;
- Shefer, Guy;
- Tolkien, Zoe;
- Usher-Smith, Juliet;
- Walker, Matthew;
- Danesh, John;
- Griffin, Simon
Publication type:
journal article
Genome-wide analysis of blood lipid metabolites in over 5000 South Asians reveals biological insights at cardiometabolic disease loci.
Published in:
2021
By:
- Harshfield, Eric L.;
- Fauman, Eric B.;
- Stacey, David;
- Paul, Dirk S.;
- Ziemek, Daniel;
- Ong, Rachel M. Y.;
- Danesh, John;
- Butterworth, Adam S.;
- Rasheed, Asif;
- Sattar, Taniya;
- Zameer-ul-Asar;
- Saleem, Imran;
- Hina, Zoubia;
- Ishtiaq, Unzila;
- Qamar, Nadeem;
- Mallick, Nadeem Hayat;
- Yaqub, Zia;
- Saghir, Tahir;
- Rizvi, Syed Nadeem Hasan;
- Memon, Anis
Publication type:
journal article
GUESS-ing Polygenic Associations with Multiple Phenotypes Using a GPU-Based Evolutionary Stochastic Search Algorithm.
Published in:
PLoS Genetics, 2013, v. 9, n. 8, p. 1, doi. 10.1371/journal.pgen.1003657
By:
- Bottolo, Leonardo;
- Chadeau-Hyam, Marc;
- Hastie, David I.;
- Zeller, Tanja;
- Liquet, Benoit;
- Newcombe, Paul;
- Yengo, Loic;
- Wild, Philipp S.;
- Schillert, Arne;
- Ziegler, Andreas;
- Nielsen, Sune F.;
- Butterworth, Adam S.;
- Ho, Weang Kee;
- Castagné, Raphaële;
- Munzel, Thomas;
- Tregouet, David;
- Falchi, Mario;
- Cambien, François;
- Nordestgaard, Børge G.;
- Fumeron, Fredéric
Publication type:
Article
Functional IL6R 358Ala Allele Impairs Classical IL-6 Receptor Signaling and Influences Risk of Diverse Inflammatory Diseases.
Published in:
PLoS Genetics, 2013, v. 9, n. 4, p. 1, doi. 10.1371/journal.pgen.1003444
By:
- Ferreira, Ricardo C.;
- Freitag, Daniel F.;
- Cutler, Antony J.;
- Howson, Joanna M. M.;
- Rainbow, Daniel B.;
- Smyth, Deborah J.;
- Kaptoge, Stephen;
- Clarke, Pamela;
- Boreham, Charlotte;
- Coulson, Richard M.;
- Pekalski, Marcin L.;
- Wei-Min Chen;
- Onengut-Gumuscu, Suna;
- Rich, Stephen S.;
- Butterworth, Adam S.;
- Malarstig, Anders;
- Danesh, John;
- Todd, John A.
Publication type:
Article
Association of shorter leucocyte telomere length with risk of frailty.
Published in:
Journal of Cachexia, Sarcopenia & Muscle, 2022, v. 13, n. 3, p. 1741, doi. 10.1002/jcsm.12971
By:
- Bountziouka, Vasiliki;
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- Wang, Qingning;
- Musicha, Crispin;
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- Kaptoge, Stephen;
- Di Angelantonio, Emanuele;
- Butterworth, Adam S.;
- Thompson, John R.;
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- Danesh, John N.;
- Harvey, Nicholas C.;
- Cooper, Cyrus;
- Samani, Nilesh J.
Publication type:
Article
An empirical investigation into the impact of winner's curse on estimates from Mendelian randomization.
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International Journal of Epidemiology, 2023, v. 52, n. 4, p. 1209, doi. 10.1093/ije/dyac233
By:
- Jiang, Tao;
- Gill, Dipender;
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Publication type:
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204Effects of adiposity on the human proteome: Mendelian randomization study using individual-level data.
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International Journal of Epidemiology, 2021, v. 50, p. 1, doi. 10.1093/ije/dyab168.235
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- Timpson, Nicholas
Publication type:
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High-throughput multivariable Mendelian randomization analysis prioritizes apolipoprotein B as key lipid risk factor for coronary artery disease.
Published in:
2021
By:
- Zuber, Verena;
- Gill, Dipender;
- Ala-Korpela, Mika;
- Langenberg, Claudia;
- Butterworth, Adam;
- Bottolo, Leonardo;
- Burgess, Stephen
Publication type:
journal article
Network Mendelian randomization: using genetic variants as instrumental variables to investigate mediation in causal pathways.
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International Journal of Epidemiology, 2015, v. 44, n. 2, p. 484, doi. 10.1093/ije/dyu176
By:
- Burgess, Stephen;
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Publication type:
Article
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers.
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Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46834-3
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- Schioth, Helgi B.;
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- Pietzner, Maik;
- Langenberg, Claudia;
- Atkins, Joshua;
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- Sirui Zhou;
- Richards, Brent J.;
- Yarmolinsky, James;
- Martin, Richard M.;
- Borlido, Joana;
- Mu, Xinmeng J.;
- Butterworth, Adam
Publication type:
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Lipid-Related Markers and Cardiovascular Disease Prediction.
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JAMA: Journal of the American Medical Association, 2012, v. 307, n. 23, p. 2499, doi. 10.1001/jama.2012.6571
By:
- Di Angelantonio, Emanuele;
- Cao, Pei;
- Pennells, Lisa;
- Kaptoge, Stephen;
- Caslake, Muriel;
- Thompson, Alexander;
- Butterworth, Adam S.;
- Sarwar, Nadeem;
- Wormser, David;
- Saleheen, Danishn;
- Ballantyne, Christie M.;
- Psaty, Bruce M.;
- SundstrÃ¶m, Johan;
- Ridker, Paul M.;
- Nagel, Dorothea;
- Gillum, Richard F.;
- Ford, Ian;
- Ducimetiere, Pierre;
- Kiechl, Stefan;
- Koenig, Wolfgang
Publication type:
Article
Association of dietary, circulating, and supplement fatty acids with coronary risk: a systematic review and meta-analysis.
Published in:
2014
By:
- Chowdhury, Rajiv;
- Warnakula, Samantha;
- Kunutsor, Setor;
- Crowe, Francesca;
- Ward, Heather A;
- Johnson, Laura;
- Franco, Oscar H;
- Butterworth, Adam S;
- Forouhi, Nita G;
- Thompson, Simon G;
- Khaw, Kay-Tee;
- Mozaffarian, Dariush;
- Danesh, John;
- Di Angelantonio, Emanuele
Publication type:
journal article
Association of Dietary, Circulating, and Supplement Fatty Acids With Coronary Risk.
Published in:
Annals of Internal Medicine, 2014, v. 160, n. 6, p. 398, doi. 10.7326/M13-1788
By:
- Chowdhury, Rajiv;
- Warnakula, Samantha;
- Kunutsor, Setor;
- Crowe, Francesca;
- Ward, Heather A.;
- Johnson, Laura;
- Franco, Oscar H.;
- Butterworth, Adam S.;
- Forouhi, Nita G.;
- Thompson, Simon G.;
- Kay-Tee Khaw;
- Mozaffarian, Dariush;
- Danesh, John;
- Di Angelantonio, Emanuele
Publication type:
Article
Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis.
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European Heart Journal, 2014, v. 35, n. 9, p. 578, doi. 10.1093/eurheartj/eht367
By:
- Kaptoge, Stephen;
- Seshasai, Sreenivasa Rao Kondapally;
- Gao, Pei;
- Freitag, Daniel F.;
- Butterworth, Adam S.;
- Borglykke, Anders;
- Di Angelantonio, Emanuele;
- Gudnason, Vilmundur;
- Rumley, Ann;
- Lowe, Gordon D.O.;
- Jørgensen, Torben;
- Danesh, John
Publication type:
Article
Association of Multiple Biomarkers of Iron Metabolism and Type 2 Diabetes: The EPIC-InterAct Study.
Published in:
2016
By:
- Podmore, Clara;
- Meidtner, Karina;
- Schulze, Matthias B.;
- Scott, Robert A.;
- Ramond, Anna;
- Butterworth, Adam S.;
- Di Angelantonio, Emanuele;
- Danesh, John;
- Arriola, Larraitz;
- Barricarte, Aurelio;
- Boeing, Heiner;
- Clavel-Chapelon, Françoise;
- Cross, Amanda J.;
- Dahm, Christina C.;
- Fagherazzi, Guy;
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- Gavrila, Diana;
- Grioni, Sara;
- Gunter, Marc J.;
- Gusto, Gaelle
Publication type:
journal article
Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer's disease.
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PLoS Genetics, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.pgen.1010294
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- Paranjpe, Manish D.;
- Chaffin, Mark;
- Zahid, Sohail;
- Ritchie, Scott;
- Rotter, Jerome I.;
- Rich, Stephen S.;
- Gerszten, Robert;
- Guo, Xiuqing;
- Heckbert, Susan;
- Tracy, Russ;
- Danesh, John;
- Lander, Eric S.;
- Inouye, Michael;
- Kathiresan, Sekar;
- Butterworth, Adam S.;
- Khera, Amit V.
Publication type:
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Mendelian Randomization Analysis With Multiple Genetic Variants Using Summarized Data.
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Genetic Epidemiology, 2013, v. 37, n. 7, p. 658, doi. 10.1002/gepi.21758
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