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- Title
Systemic Lupus Erythematosus as a Cause of First-episode Psychosis in the Second Trimester of Pregnancy.
- Authors
Siu, B. W. M.; Chow, H. M. T.; Kwok, S. S. P.; Li, O. L.; Koo, M. L.; P. W.
- Abstract
A Chinese woman had a first-episode of psychosis in the second trimester of pregnancy. The sudden onset of psychotic symptoms and fluctuating mental condition with visual hallucinations suggested an organic origin for the psychosis. Antipsychotic medication was started. Ultrasound investigation at 19 weeks of gestation revealed intrauterine growth retardation and she decided to terminate the pregnancy. Positive blood test results for antiphospholipid antibodies confirmed a diagnosis of systemic lupus erythematosus with antiphospholipid syndrome. Psychosis is one of the neuropsychiatric syndromes in systemic lupus erythematosus and can sometimes be the primary manifestation, antedating other evidence of the disease. Pregnancy can exacerbate systemic lupus erythematosus. This report highlights the importance of considering an organic cause for psychosis, including systemic lupus erythematosus, especially when it occurs for the first time during pregnancy in a previously healthy woman.
- Subjects
SYSTEMIC lupus erythematosus; PSYCHOSES; SECOND trimester of pregnancy; PREGNANCY &; psychology; PHOSPHOLIPID antibodies; PSYCHOLOGICAL research; PHYSIOLOGY; PATIENTS
- Publication
East Asian Archives of Psychiatry, 2010, Vol 20, Issue 3, p145
- ISSN
2078-9947
- Publication type
Article