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- Title
Collagenous colitis associated with novel sprue-like intestinal diseases.
- Authors
Freeman, Hugh J.
- Abstract
Almost a half-century ago, an unusual and distinct form of colitis was first recognized, collagenous colitis, characterized by subepithelial trichrome-positive deposits having the ultrastructural features of collagen. Later, other reports documented more extensive collagenous dis-ease in these patients, sometimes in the stomach and small bowel, a close linkage with other forms of microscopic colitis and its association with celiac and other immune-mediated diseases. Moreover, emerging genetic methods permitted large studies of collagenous colitis to complement these intriguing clinical and pathological studies. Finally, recent and related studies have further demonstrated these immune-based forms of colitis, with new sprue-like intestinal diseases caused by novel medications, recently detected viral infections and vaccinations.
- Subjects
TROPICAL sprue; CELIAC disease; INTESTINAL diseases; VIRUS diseases; HUMAN microbiota; COLITIS; IMMUNOLOGIC diseases; DISEASE complications
- Publication
Gastroenterology & Hepatology from Bed to Bench, 2023, Vol 16, Issue 2, p145
- ISSN
2008-2258
- Publication type
Article
- DOI
10.22037/ghfbb.v16i2.2698