We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Aerobic Training Improves Angiogenic Potential Independently of VEGF Modifications in Postmenopausal Woman.
- Authors
Di Baldassarre, Angela; Izzicupo, Pascal; Ghinassi, Barbara; D'Amico, Maria Angela; Nakamura, Fabio
- Abstract
Purpose: To evaluate the effect of walking-training on serum angiogenic potential in postmenopausal women. Materials and Methods: Thirty-four postmenopausal women (56.18 ± 4.24 yr) participated in a 13 weeks program of walking-training. Anthropometric measures, VEGF, IL-1α, IL-1ß, IL-2, IL-8, IL-10, IL-12p70, TNF-α, C-reactive protein, insulin, IGF-1, cortisol, DHEA-S, leptin, visfatin, resistin and adiponectin were evaluated before and after training. Moreover, serum samples were tested for their ability to chemo – attract endothelial cells and to support the in vitro formation of capillary – like structures. Results: After training, the levels of IL-8, TNF-α, leptin and resistin were significantly lower, levels of DHEA-S and adiponectin increased, serum angiogenic properties improved, whereas no changes in anthropometric parameters or VEGF were detected. Conclusions: Walking training reduces inflammatory status and leads to a significant improvement in serum angiogenic properties in the absence of modifications in body composition and VEGF level.
- Subjects
AEROBIC exercises; POSTMENOPAUSE; C-reactive protein
- Publication
Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia, 2017, Vol 122, p76
- ISSN
1122-6714
- Publication type
Abstract