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- Title
Fine-needle aspiration of cystic parotid glands lesions: an institutional review of 46 cases with histologic correlation.
- Authors
Nasuti, Joseph F.; Yu, Gordon H.; Gupta, Prabodh K.; Nasuti, J F; Yu, G H; Gupta, P K
- Abstract
<bold>Background: </bold>Many case reports describing various benign and malignant disease entities diagnosed in cystic parotid gland lesions by fine-needle aspiration (FNA) exist in the literature. Very few studies, however, discuss the efficacy and the diagnostic difficulties of FNA cytology in such lesions. The authors report a 5-year institutional experience with FNA cytology of cystic parotid gland lesions and address the accuracy of the procedure and avoidance of diagnostic pitfalls.<bold>Methods: </bold>A retrospective review of 46 cases in which patients clinically presented with cystic parotid gland lesions was done from a total of 221 parotid FNAs performed over a 5-year period at the University of Pennsylvania Medical Center. The clinical features, cytology, and follow-up surgical pathology were reviewed to determine diagnostic accuracy and highlight potential pitfalls.<bold>Results: </bold>Based on subsequent surgical excision in 29 of the 46 cases of cystic parotid gland lesions, a diagnostic accuracy rate of 83% was obtained for FNA. Approximately 20% (9 of 46 cases) were found to be clinically significant tumors and included 4 mucoepidermoid and 1 adenocarcinoma (NOS), 3 benign mixed tumors, and 1 metastatic melanoma. Three major factors were implicated as diagnostic pitfalls in our series: 1) failure to obtain critical clinical information, 2) overinterpretation of paucicellular specimens, and 3) failure to realize that certain tumors generally perceived as solid masses can present clinically as cystic lesions.<bold>Conclusions: </bold>FNA cytology is a valuable tool in the primary diagnosis and management of cystic parotid gland lesions. The diagnostic accuracy of this procedure can be significantly improved by acquiring a detailed clinical history, obtaining an adequate cellular specimen, and having knowledge of the variety and frequencies of possible diagnostic entities that may present as cystic parotid gland lesions.
- Subjects
CYSTS (Pathology); PAROTID gland diseases; NEEDLE biopsy
- Publication
Cancer (0008543X), 2000, Vol 90, Issue 2, p111
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/(SICI)1097-0142(20000425)90:2<111::AID-CNCR6>3.0.CO;2-N