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- Title
The role of positron emission tomography in the evaluation of myocardial ischemia in women.
- Authors
Taqueti, Viviany; Dorbala, Sharmila; Taqueti, Viviany R
- Abstract
Cardiovascular disease continues to be the number one cause of death in women, yet most women are unaware of their risk. Over the last decade, radionuclide myocardial perfusion imaging with positron emission tomography (PET) has become a powerful tool for the diagnosis and risk stratification of patients with known or suspected coronary artery disease (CAD). This editorial viewpoint will review the maturing role of PET imaging in women, particularly as applied to the evaluation of ischemic heart disease. Specifically, we focus on distinct advantages offered by PET imaging in the evaluation of myocardial ischemia in women: (1) improved diagnostic accuracy, including in the presence of breast or adipose tissue and small left ventricular cavity size, (2) decreased radiation exposure through the use of short-lived radiopharmaceuticals, and (3) the ability to quantify myocardial blood flow and coronary flow reserve to diagnose ischemia, even in the absence of obstructive CAD. As such, cardiac PET perfusion imaging stands to play a unique role in defining the diagnosis and prognosis of women with ischemic heart disease, while also guiding new treatment strategies for their more prevalent cardiovascular disease phenotypes.
- Subjects
CORONARY disease; POSITRON emission tomography; WOMEN'S health; CAUSES of death; CARDIOGRAPHIC tomography; ADIPOSE tissues; CORONARY heart disease complications; DIAGNOSTIC imaging; EXERCISE tests; HEART function tests; PROGNOSIS; RESEARCH evaluation; VASODILATORS
- Publication
Journal of Nuclear Cardiology, 2016, Vol 23, Issue 5, p1008
- ISSN
1071-3581
- Publication type
journal article
- DOI
10.1007/s12350-016-0603-3