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- Title
Nanofibrous Scaffolds for the Management of Periodontal Diseases.
- Authors
Mansour, Alaa M.; El-Sherbiny, Ibrahim M.
- Abstract
Periodontium is an intricate complex system that consists of different types of tissues. There are several diseases that affect periodontium causing destruction and loss of its tissues. The goal for periodontal treatment is the reconstruction of the lost periodontal tissues. Periodontal regeneration is considered one of oral health care challenges, and it can depend on using nanostructured biomaterials. These nanostructured biomaterials simulate the microenvironment of the extracellular matrix (ECM) and act as a biomimetic platform to attract stem cells and stimulate their differentiation to specific lineages. There are different forms for nanostructured biomaterials such as nanofibers and nanoparticles. Nanofibers have a similar structure and size to those of the natural collagen seen in the ECM of periodontal tissues. This chapter gives a brief overview of periodontium and periodontal diseases. Moreover, it discusses the different strategies for periodontal therapy including periodontal tissue regeneration and the recent nanofibrous biomaterials that can be used for periodontal regeneration.
- Subjects
DISEASE management; PERIODONTAL disease; BIOMATERIALS; GUIDED tissue regeneration; CELL differentiation; PERIODONTIUM
- Publication
Advances in Polymer Science, 2023, Vol 291, p361
- ISSN
0065-3195
- Publication type
Article
- DOI
10.1007/12_2022_126