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- Title
Voclosporin is on the table, let's taste it.
- Authors
Pernaute, Olga Sánchez
- Abstract
The article offers information on voclosporin, a novel calcineurin inhibitor (CNI). Topics discussed include characterization of calcineurin, CNIs as a treatment for extrarenal disease, the potential of calcineurin to dephosphorylate intracellular molecules, synthesis of voclosporin and the efficacy of voclosporin as a treatment for lupus nephritis.
- Subjects
HYDROLASES; LUPUS nephritis; IMMUNOSUPPRESSIVE agents; T cells; ENZYME inhibitors; CYCLOSPORINE; ANTIRHEUMATIC agents; TRANSCRIPTION factors; DRUG approval; DRUG efficacy; CELL receptors; PHARMACODYNAMICS; CHEMICAL inhibitors
- Publication
Rheumatology, 2024, Vol 63, Issue 7, p1762
- ISSN
1462-0324
- Publication type
Editorial
- DOI
10.1093/rheumatology/keae016