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- Title
GLICOSE SALIVAR: ASSOCIAÇÃO COM PARÂMETROS GLICO-LIPÊMICOS E QUANTIFICAÇÃO POR FT-IR EM TRABALHADORES RURAIS.
- Authors
Pappen Umpierres, Rosileidi; Hedwig Pohl, Hildegard; Antonio Corbellini, Valeriano
- Abstract
A new method based on Fourier Transform Infrared Molecular Absorption Spectroscopy (FT-IR) and chemometrics was developed for the quantification of salivary glucose using saliva and blood samples from 104 rural workers from five municipalities of Rio Pardo Valley-RS, Brazil. The most relevant finding of the glyco-lipemic profile was the higher prevalence of elevated levels of total cholesterol and HDL in women (p<0.05). Hypertriglyceridemia was also more prevalent in women considering only values above the desirable maximum limit (1.0509 mmol.L-1). Salivary glucose ranged from 0 to 0.7221 mmol.L-1 and showed no significant correlation with the glyco-lipemic parameters evaluated. Partial least squares regression analysis between the first derivative salivary spectra acquired by the (SRIFTS) Specular Reflect technique and the respective salivary glucose values assessed by the enzymatic method gave rise to a chemometric model with good predictive quality (RMSECV=0,0007; RMSEP = 0,0009, R²=0,999990, p <0.0001). Therefore, it is concluded that the use of salivary glucose does not appear as a suitable biomarker to evaluate glyco-lipemic profile in rural workers. On the other hand, it can be easily estimated by FT-IR using a chemometric method.
- Subjects
BRAZIL; MOLECULAR spectroscopy; INFRARED absorption; HDL cholesterol; FOURIER transforms; SEPARATION of variables
- Publication
Revista Brasileira de Obesidade, Nutrição e Emagrecimento, 2024, Vol 18, Issue 114, p496
- ISSN
1981-9919
- Publication type
Article