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- Title
Herpes simplex virus type 2 prevalence of epidemic proportions in rural Zimbabwean women: association with other sexually transmitted infections.
- Authors
Kjetland, Eyrun; Gwanzura, Lovemore; Ndhlovu, Patricia; Mduluza, Takafira; Gomo, Exnevia; Mason, Peter; Midzi, Nicholas; Friis, Henrik; Gundersen, Svein
- Abstract
Introduction: Syndromic management of sexually transmitted infections (STIs) is one important strategy in human immunodeficiency virus (HIV) prevention in developing countries, but there is a scarcity of rural community-based data on the relative prevalences of the STIs. We sought to determine the prevalences of the STIs and their clinical correlates in rural Zimbabwean women. Methods: A cross-sectional study was conducted among 527 sexually active, non-pregnant, non-menopausal women between the ages of 20 and 49 years. Results: The seroprevalence for herpes simplex virus type 2 (HSV-2), HIV, trichomoniasis and syphilis were 64.5,29.3,24.7 and 6.2% respectively. HSV-2 seropositivity was significantly associated with current non-syphilitic ulcers (adjusted odds ratio [OR] 4.91, 95% confidence interval [CI] 1.08- 22.34.,p = 0.040). HSV-2 seroprevalence peaked at the age of 35 whereas HIV peaked at 25. The two diseases were strongly associated (OR 2.92, 95% CI 1.85-4.65, p < 0.001). Conclusion: There is evidence of rural epidemics of both HSV-2 and HIV, and a change in the aetiology of genital ulcers in rural Zimbabwe.
- Subjects
HIV; SEXUALLY transmitted diseases; SYPHILIS; SKIN infections; ULCERS; HERPESVIRUS diseases
- Publication
Archives of Gynecology & Obstetrics, 2005, Vol 272, Issue 1, p67
- ISSN
0932-0067
- Publication type
Article
- DOI
10.1007/s00404-004-0689-8