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- Title
Clinical relevance of immunohistochemical staining for ecto‐AMPase and ecto‐ATPase in chronic allograft nephropathy (CAN).
- Authors
Mui, Kwok W.; van Son, Willem J.; Tiebosch, Anton T. M. G.; van Goor, Harry; Bakker, Winston W.
- Abstract
Introduction. Chronic allograft nephropathy (CAN) is a major cause of deterioration of kidney function in transplanted patients. It is thought that glomerular ischaemia may contribute to glomerular dysfunction and proteinuria in these subjects. As reduced expression of glomerular ecto‐ATPase concurrent with upregulation of glomerular ecto‐AMPase activity is associated with local ischaemia, we compared the expression of these glomerular ecto‐enzymes in kidney biopsies from subjects with CAN or with acute rejection vs normal human kidney tissue.
- Publication
Nephrology Dialysis Transplantation, 2003, Vol 18, Issue 1, p158
- ISSN
0931-0509
- Publication type
Article
- DOI
10.1093/ndt/18.1.158