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- Title
Neuromelanin? MRI of Noradrenergic and Dopaminergic Neurons.
- Authors
Watanabe, Takashi
- Abstract
Increased signal intensity in magnetic resonance imaging, however, can theoretically not be ascribed to specific molecules (except water) when T1 of the tissue with the molecules is prolonged. These indicate not NM but the high proton density of NA neurons is the contrast source. This observation of longer T1 and higher proton density in LC than in adjacent brain regions was confirmed by the authors as well.[[3]] Nevertheless, the authors maintain that this is imaging of the neuromelanin (NM).
- Subjects
DOPAMINERGIC neurons; NORADRENERGIC neurons; LOCUS coeruleus; MAGNETIC resonance imaging; MAGNETIZATION transfer
- Publication
Journal of Magnetic Resonance Imaging, 2023, Vol 58, Issue 1, p328
- ISSN
1053-1807
- Publication type
Article
- DOI
10.1002/jmri.28479