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- Title
Association of Physical Activity History With Physical Function and Mortality in Old Age.
- Authors
Stenholm, Sari; Koster, Annemarie; Valkeinen, Heli; Patel, Kushang V.; Bandinelli, Stefania; Guralnik, Jack M.; Ferrucci, Luigi
- Abstract
<bold>Background: </bold>We examined whether physical activity in early adulthood, late midlife, and old age as well as cumulative physical activity history are associated with changes in physical functioning and mortality in old age.<bold>Methods: </bold>Data are from participants aged 65 years or older enrolled in the InCHIANTI study who were followed up from 1998-2000 to 2007-2008 (n = 1,149). At baseline, participants recalled their physical activity levels at ages 20-40, 40-60, and in the previous year, and they were categorized as physically inactive, moderately active, and physically active. Physical performance was assessed with the Short Physical Performance Battery and self-reported mobility disability was evaluated at the 3-, 6- and 9-year follow-up. Mortality follow-up was assessed until the end of 2010.<bold>Results: </bold>Physical inactivity at baseline was associated with greater decline in Short Physical Performance Battery score (mean 9-year change: -2.72, 95% CI: -3.08, -2.35 vs -0.98, 95% -1.57, -0.39) and greater rate of incident mobility disability (hazard ratio 4.66, 95% CI 1.14-19.07) and mortality (hazard ratio 2.18, 95% CI 1.01-4.70) compared to physically active participants at baseline. Being physically active throughout adulthood was associated with smaller decline in physical performance as well as with lower risk of incident mobility disability and premature death compared with those who had been less active during their adult life.<bold>Conclusions: </bold>Higher cumulative physical activity over the life course was associated with less decline in physical performance and reduced rate of incident mobility disability and mortality in older ages.
- Subjects
ITALY; OLDER people physiology; HEALTH of older people; MOBILITY of older people; PHYSICAL activity -- Social aspects; HEALTH management; GERIATRIC assessment; AGING; MORTALITY; MOTOR ability; RESEARCH funding; SYMPTOMS; LIFESTYLES
- Publication
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2016, Vol 71, Issue 4, p496
- ISSN
1079-5006
- Publication type
journal article
- DOI
10.1093/gerona/glv111