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- Title
The Determination of Prostate-Specific Antigen (PSA) in Human Female Sera by Means of a Sensitive ELISA.
- Authors
Hagendorff, G.; Schuft-Werners, P.; Stibbe, W.; Mast, W.-P.; Scheit, K. H.
- Abstract
The development of a sensitive sandwich ELISA for the determination of prostate-specific antigen in serum is reported. The assay makes use of the monoclonal antibodies mAB43A2 and mAB28A4. The analysis of 231 sera from female patients with the tentative diagnosis of breast cancer yielded in 31 cases PSA concentrations above the detection limit of the assay (0.08 µg/l). Serum PSA should therefore not further be regarded as an absolutely specific marker of prostatic tissue.
- Publication
Journal of Laboratory Medicine / Laboratoriums Medizin, 1996, Vol 20, Issue 5, p301
- ISSN
0342-3026
- Publication type
Article