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- Title
环境光导致昼夜节律紊乱对睡眠的影响.
- Authors
陈钧; 杜莉; 王佩; 魏虹; 韩祖成
- Abstract
Objective: To study the effects of circadian disruption by environmental light on sleep. Methods: Disrupting the circadian clock by altered light-dark cycles (a shortened 20 h day, 10 h light, 10 h dark; LD10:10), we used mouse sleeping analysis system to record electroencephalogram and electromyogram, to analyze sleeping and awaking time in a day, delta power of sleeping and awaking waves in different time,and times of sleeping and awaking switchover. Results: Environmental circadian disruption by light caused loss of normal day-night differences in wake, non-rapid eye movement sleep (NREM), and rapid eye movement sleep (REM) (P > 0.05) between light and dark phases. Circadian disruption increased the number of transitions between wake and NREM (P<0.05). Environmental circadian disruption by light abolished the normally observed decrease in delta power at the onset of the light phase (P>0.05). Conclusion: Our results demonstrate that this model of circadian disruption did not lead to marked sleep deprivation, but instead affected the timing and quality of sleep.
- Publication
Progress in Modern Biomedicine, 2015, Vol 15, Issue 31, p6046
- ISSN
1673-6273
- Publication type
Article
- DOI
10.13241/j.cnki.pmb.2015.31.013