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- Title
Synthesis of 3-oxoesters and functional derivatives of pyrimidin-4(3 Н)-one based on 1-(2,6-dihalophenyl)cyclopropan-1-carboxylic acids.
- Authors
Novakov, I.; Yablokov, A.; Navrotskii, M.; Mkrtchyan, A.; Vernigora, A.; Babushkin, A.; Kachala, V.; Ruchko, E.
- Abstract
Special features of the synthesis and chemical transformations of novel functional derivatives of 6-[1-(2,6-dihalophenyl)cyclopropyl]pyrimidin-4(3 H)-one and ethyl esters of 3-[1-(2,6-dihalophenyl)cyclopropyl]-2-methyl-3-oxopropanoic acids prepared from 2-(2,6-dihalophenyl)acetonitriles have been revealed. Novel achiral structural analogs of experimental anti-HIV agent МС-1501 have been synthesized.
- Subjects
CHEMICAL amplification; ETHYL esters; ACETONITRILE; ANTI-HIV agents; ORGANIC synthesis
- Publication
Russian Journal of General Chemistry, 2017, Vol 87, Issue 2, p224
- ISSN
1070-3632
- Publication type
Article
- DOI
10.1134/S1070363217020128