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- Title
Diffuse Sclerosing Variant of Thyroid Carcinoma Presenting as Hashimoto Thyroiditis: A Case Report.
- Authors
Vukasović, Anamarija; Kuna, Sanja Kusačić; Ostović, Karmen Trutin; Prgomet, Drago; Banek, Tomislav
- Abstract
The aim of report is to present a case of a rare diffuse sclerosing variant of a papillary thyroid carcinoma. A 15- year old girl referred for ultrasound examination because of painless thyroid swelling lasting 10 days before. An ultrasound of the neck showed diffusely changed thyroid parenchyma, without nodes, looking as lymphocytic thyroiditis Hashimoto at first, but with »snow-storm« appearance, predominantly in the right lobe. Positive thyroid peroxidase antibodies (TPO-AT) also suggested Hashimoto thyroiditis. Repeated US-FNAB (fine needle-aspiration biopsy) of the right lobe re-vealed diffuse sclerosing variant of papillary thyroid carcinoma and patient underwent total thyreoidectomy. Patohisto-logic finding confirmed diffuse sclerosing variant of a papillary thyroid carcinoma in the both thyroid lobes and several metastatic lymph nodes. Two months later patient recived radioablative therapy with 3700 MBq (100 mCi) of 1-131 fol-lowed by levothyroxine replacement. At the moment, patient is without evidence of local or distant metastases and next regular control is scheduled in 6 months. In conclusion, a diffuse sclerosing variant is rare form of papillary thyroid car-cinoma that echographically looks similar to Hashimoto thyroiditis and sometimes could be easily overlooked.
- Subjects
THYROID cancer; THYROIDITIS; ULTRASONIC imaging of cancer; PEROXIDASE; METASTASIS; THYROID gland surgery
- Publication
Collegium Antropologicum, 2012, Vol 36, p219
- ISSN
0350-6134
- Publication type
Article