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- Title
Exploring the Effect of Repetitive Transcranial Magnetic Stimulation over the Supplementary Motor Cortex on the Clinical-Cognitive Symptoms of Patients with the Obsessive-Compulsive Disorder.
- Authors
Rostami, Reza
- Abstract
Objective: The present study was conducted aimed at investigating the effect of the transcranial magnetic stimulation on reducing the clinical and cognitive symptoms of patients with the obsessive-compulsive disorder (OCD). Methods and Materials: In a single-blind experiment, 35 OCD patients of Atieh Clinical Neuroscience Center were randomly selected for the study. The patients received 1Hz rTMS over the supplementary motor cortex for 10 sessions. Before and after the treatment, Yale-Brown obsessive-compulsive scale (YBOCS) and Cambridge Neuropsychological Test Automated Battery (CANTAB) were utilized to assess the patients' clinical symptoms, attention, memory and executive functions. Results: The analysis of the results indicated that rTMS improved obsessive-compulsive symptoms (P<0.001), executive functions (P<0.001), attention (P<0.03), and the spatial working memory (P<0.02). From among the patients, 20 of them (57%) responded to the treatment and 4 patients (11.42%) demonstrated remission. Conclusion: The results of the study demonstrated that rTMS can be used as a new treatment for the clinical and cognitive symptoms of OCD patients.
- Subjects
BROWN University; YALE University; TRANSCRANIAL magnetic stimulation; MOTOR cortex; OBSESSIVE-compulsive disorder; NEUROPSYCHOLOGICAL tests; SPATIAL memory
- Publication
Iranian Journal of Psychiatry & Behavioral Sciences / Progress in Psychiatry & Behavioral Sciences, 2018, p163
- ISSN
1735-8639
- Publication type
Article