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- Title
Formula fed twin infants with recurrent hypocalcemic seizures with vitamin D deficient rickets and hyperphosphatemia.
- Authors
Byung Wook Jo; Ye Jee Shim; Jin Hyeok Choi; Jun Sik Kim; Hee Joung Lee; Heung Sik Kim
- Abstract
Vitamin D deficient rickets is generally known to occur in breast fed infants. And excessive phosphate ingestion is a main cause of late onset hypocalcemia in formula fed infants. Here we introduce 45-day-old formula fed hypocalcemic twins with recurrent seizure attacks. They were diagnosed as having both of vitamin D deficient rickets and hyperphosphatemia. Radiologic findings indicated mild rickets and the twins were treated with calcium and alfacalcidol. After 3-5 months of oral supplementation, medication was discontinued in both twins. They showed normal growth and calcium, phosphorus, and vitamin D levels during the 6-month follow-up period. Twins can be at risk for hypocalcemia because of their high risk of vitamin D deficiency, low birth weight, and premature birth. Therefore twin pregnant women need ingestion of sufficient vitamin D and calcium.
- Subjects
VITAMIN D deficiency; RICKETS; HYPERPHOSPHATEMIA; INFANT formulas; DISEASES in twins
- Publication
Annals of Pediatric Endocrinology & Metabolism, 2015, Vol 20, Issue 2, p102
- ISSN
2287-1012
- Publication type
Case Study
- DOI
10.6065/apem.2015.20.2.102