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- Title
Ethics of the use of placebos in clinical research: a proposal for decision-making algorithms.
- Authors
Guerreiro Fregnani, José Humberto Tavares; Carvalho, André Lopes; Paranhos, Flávio Rocha Lima; de Souza Viana, Luciano; Serrano, Sérgio Vicente; Cárcano, Flávio; Ferreira, João Fernando Monteiro; Zier, Sandra Solci; Gontijo, Pollyana Anício Magalhães; Stefanoff, Cláudio Gustavo; França, Paulo Henrique Condeixa; de Almeida Bendati, Maria Mercedes; Marodin, Gabriela; de Almeida Venâncio, Jorge Alves
- Abstract
The use of placebos in clinical research has been a matter of considerable debate in recent years, notably when the World Medical Association published, in 2002, a note of clarification for paragraph 29 of the Helsinki Declaration. Brazil is known for its strong opposition to the flexible use of placebos. Both the Federal Council of Medicine and the National Health Council have published resolutions regulating the use of placebos in Brazil, preventing their use if there is a more effective therapeutic method already in place. The present study reinforces that position and aims to describe the various uses of placebos in clinical research, as well as examining the complex decisions relating to the ethics of their use. Additionally, the authors propose a reflection on the use of placebos through decision-making algorithms based on Brazilian ethical standards.
- Subjects
BIOETHICS; MEDICAL research; PLACEBOS
- Publication
Revista Bioetica, 2015, Vol 23, Issue 3, p456
- ISSN
1983-8042
- Publication type
Article
- DOI
10.1590/1983-80422015233082