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- Title
Green chemistry approach for silver nanoparticles synthesis from Halimeda macroloba and their potential medical and environmental applications.
- Authors
Lavanya, G.; Anandaraj, K.; Gopu, M.; Selvam, K.; Selvankumar, T.; Govarthanan, M.; Kumar, P.
- Abstract
This study aims to synthesize silver nanoparticles (AgNPs) using Halimeda macroloba extract and assess their anticancer and photocatalytic properties. Ultraviolet–visible spectrophotometry (UV–visible), Fourier transform infrared (FT-IR) spectroscopy, Transmission electron microscope (TEM), scanning electron microscope-energy-dispersive spectroscopy (SEM–EDX), X-ray photoelectron spectroscopy (XPS), and particle-size distribution (PSD) were used to characterize the synthesized AgNPs. The green-synthesized AgNPs to be spherical in shape with a size of about 50–100 nm. The half-maximal inhibitory concentration (IC50) for AgNPs was determined to be 89.5 g/mL against the human hepatoma cell line (Huh-7). Fluorescent microscopy was used to evaluate the morphological alterations of Huh-7 cells stained with acridine orange/ethidium bromide (AO/EtBr), 2′-7′dichlorofluorescin diacetate (DCFH-DA), and rhodamine 123. Meanwhile, AgNPs exhibited 91.35% photocatalytic activity against methylene blue (MB) after 100 min of exposure to sunlight. Therefore, AgNPs have a strong potential for usage in anticancer activities and photocatalytic organic pollutant destruction.
- Subjects
SILVER nanoparticles; X-ray photoelectron spectroscopy; ELECTRON spectroscopy; TRANSMISSION electron microscopes; RHODAMINES; PHOTOCATALYSTS; METHYLENE blue; SUSTAINABLE chemistry; P-glycoprotein
- Publication
Applied Nanoscience, 2023, Vol 13, Issue 9, p5865
- ISSN
2190-5509
- Publication type
Article
- DOI
10.1007/s13204-023-02812-7