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- Title
Diagnostic challenges in minimal deviation adenocarcinoma of the uterine cervix: A report of two cases and review of the literature.
- Authors
FEIFEI GUO; YALI HU; XIAOFENG XU; RONG LI; TONG RU; JINGMEI WANG; HUAIJUN ZHOU
- Abstract
Minimal deviation adenocarcinoma (MDA) of the uterine cervix, otherwise known as adenoma malignum, is a rare variant of cervical adenocarcinoma, which represents a diagnostic challenge in the field of gynecologic oncology, due to its benign-resembling histological characteristics. To achieve a better understanding of this disease, we present two cases of MDA: one case presented with profuse watery discharge and cervical enlargement, accompanied by retention cysts and hardening; the other presented with a history of myoma cervicis uteri. Both patients underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy and pelvic lymphadenectomy and our follow-up indicated that the patients were still free of any disease. Subsequently, a literature review was performed and the results demonstrated that early diagnosis, clinical stage and surgical protocols are the main factors affecting the prognosis of MDA. Close follow-up of the cases may provide more information regarding this disease and the efficacy of the available therapeutic methods.
- Subjects
CERVICAL cancer diagnosis; ADENOMATOID tumors; DIAGNOSIS of cancer in female reproductive organs; VAGINAL discharge; VAGINAL hysterectomy
- Publication
Molecular & Clinical Oncology, 2013, Vol 1, Issue 5, p833
- ISSN
2049-9450
- Publication type
Case Study
- DOI
10.3892/mco.2013.144