We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Cre-loxP chromosome engineering of a targeted deletion in the mouse corresponding to the 3p21.3 region of homozygous loss in human tumours.
- Authors
Smith, Andrew J.H.; Jian Xian; Richardson, Melville; Johnstone, Karen A.; Rabbitts, Pamela H.
- Abstract
Presents a study which used Cre-loxP chromosome engineering for the deletion of approximately 370 kb in the mouse germline corresponding to the deleted region at 3p21.3 of homozygous loss in human tumors. Methodology; Characterization of the mouse chromosomes 9 region syntenic to 3p21.3; Generation of mice with germline transmission of the 3pk-Hyal1 deletion.
- Subjects
TUMORS; CHROMOSOMES; IMMUNOGLOBULINS
- Publication
Oncogene, 2002, Vol 21, Issue 29, p4521
- ISSN
0950-9232
- Publication type
Article
- DOI
10.1038/sj.onc.1205530