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- Title
APRIL polymorphism and systemic lupus erythematosus (SLE) susceptibility.
- Authors
Lee, Y. H.; Ota, F.; Kim-Howard, X.; Kaufman, K. M.; Nath, S. K.
- Abstract
Objective. Two novel non-synonymous polymorphisms of the APRIL gene, codon 67 (rs11552708) and 96 (rs3803800), were recently identified and tested for disease association. The 67G allele was reported to be associated with systemic lupus erythematosus (SLE) in a Japanese population. The aim of the study is to investigate whether the APRIL polymorphism associated with susceptibility to SLE in a Japanese population is associated with the susceptibility to SLE in other ethnic groups.
- Subjects
JAPAN; SYSTEMIC lupus erythematosus; GENETIC polymorphisms; DISEASE susceptibility; ETHNICITY
- Publication
Rheumatology, 2007, Vol 46, Issue 8, p1274
- ISSN
1462-0324
- Publication type
Article
- DOI
10.1093/rheumatology/kem093