We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Pathological splice mutations outside the invariant AG/GT splice sites of BRCA1 exon 5 increase alternative transcript levels in the 5' end of the BRCA1 gene.
- Authors
Claes, Kathleen; Vandesompele, Jo; Poppe, Bruce; Dahan, Karine; Coene, Ilse; Da Paepe, Anne; Messiaen, Ludwine
- Abstract
Presents a study that examined the prevalence of isoforms in normal tissues and cancer cell lines. Comparison on the BRCA1 exon between ovarian cancer cell line and normal ovarian tissue; Percentage of splicing mutations based on the Breast Information Core database; Background on denaturing gradient gel electrophoresis.
- Subjects
CELL lines; OVARIAN tumors; ELECTROPHORESIS
- Publication
Oncogene, 2002, Vol 21, Issue 26, p4171
- ISSN
0950-9232
- Publication type
Article
- DOI
10.1038/sj.onc.1205520