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- Title
Dietary Protein Consumption and the Risk of Type 2 Diabetes: ADose-Response Meta-Analysis of Prospective Studies.
- Authors
Fan, Mengying; Li, Yuqian; Wang, Chongjian; Mao, Zhenxing; Zhou, Wen; Zhang, Lulu; Yang, Xiu; Cui, Songyang; Li, Linlin
- Abstract
The relationship between dietary protein consumption and the risk of type 2 diabetes (T2D) has been inconsistent. The aim of this meta-analysis was to explore the relations between dietary protein consumption and the risk of T2D. We conducted systematic retrieval of prospective studies in PubMed, Embase, and Web of Science. Summary relative risks were compiled with a fixed effects model or a random effects model, and a restricted cubic spline regression model and generalized least squares analysis were used to evaluate the diet–T2D incidence relationship. T2D risk increased with increasing consumption of total protein and animal protein, red meat, processed meat, milk, and eggs, respectively, while plant protein and yogurt had an inverse relationship. A non-linear association with the risk for T2D was found for the consumption of plant protein, processed meat, milk, yogurt, and soy. This meta-analysis suggests that substitution of plant protein and yogurt for animal protein, especially red meat and processed meat, can reduce the risk for T2D.
- Subjects
TYPE 2 diabetes risk factors; DOSE-response relationship in biochemistry; MEDICAL information storage &; retrieval systems; MEDLINE; META-analysis; ONLINE information services; DIETARY proteins; REGRESSION analysis; SYSTEMATIC reviews
- Publication
Nutrients, 2019, Vol 11, Issue 11, p2783
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu11112783