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- Title
Seroprevalence of hepatitis B virus among hemodialysis patients in Busher province, southern Iran.
- Authors
Mostaghni, Amir Ahmad; Soltanian, Alireza; Moktari, Elaheh; Japoni, Sara; Mehrabani, Davood
- Abstract
Background: Hepatitis B virus (HBV) infection is still reported from adult hemodialysis units. Objectives: To determine the prevalence of anti-HBs antibody in hemodialysis patients and the correlation between levels of anti-HBs antibody with other factors. Patients and Methods: HBsAg, anti-HBs and anti-HBc antibodies level in 119 hemodialysis patients were evaluated by enzyme-linked immunosorbent assay. Results: Seroconversion (anti-HBs antibody >10 IU/L) was found in 22 patients. Minimum protective antibody level was found in patients aged > 60 years. Statistically significant correlation was not found between anti-HBs antibody and gender. Ten (8.4%) patients had abnormal ALT and/or AST. Prevalence of HBsAg, anti-HBc antibody, HBeAg and anti-HBe antibody were found in 8 (6.72%), 24 (25.16%), 2 (1.68%) and 3 (2.52%) patients, respectively. Conclusions: Periodic assessment of anti-HBs antibody level is strongly recommended in patients undergoing hemodialysis.
- Subjects
IRAN; HEPATITIS B; ACADEMIC medical centers; AGE distribution; ANALYSIS of variance; BIOMARKERS; STATISTICAL correlation; ENZYME-linked immunosorbent assay; HEMODIALYSIS patients; IMMUNOGLOBULINS; RESEARCH; DISEASE management; SEROCONVERSION; SEROPREVALENCE; DISEASE risk factors
- Publication
Hepatitis Monthly, 2011, Vol 11, Issue 3, p200
- ISSN
1735-143X
- Publication type
Article