We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis of Diazirine-Based Photoreactive Saccharin Derivatives for the Photoaffinity Labeling of Gustatory Receptors.
- Authors
Wang, Lei; Yoshida, Takuma; Muto, Yasuyuki; Murai, Yuta; Tachrim, Zetryana Puteri; Ishida, Akiko; Nakagawa, Shiori; Sakihama, Yasuko; Hashidoko, Yasuyuki; Masuda, Katsuyoshi; Hatanaka, Yasumaru; Hashimoto, Makoto
- Abstract
Saccharin is one of the most common artificial sweeteners that has a bitter taste at high concentrations. Currently, there are no detailed functional analyses of these gustatory receptors. Therefore, we designed and synthesized photoreactive saccharin derivatives that contain a (trifluoromethyl)diazirinyl moiety at the 5- or 6-position for use as functional analysis tools for photoaffinity labeling.
- Subjects
SACCHARIN; CHEMICAL derivatives; MOIETIES (Chemistry); PHOTOAFFINITY labeling; PHOTOCHEMISTRY techniques
- Publication
European Journal of Organic Chemistry, 2015, Vol 2015, Issue 14, p3129
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.201500184