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- Title
INFLUENCE OF ALKYLPHENOLS AND TRACE ELEMENTS IN TOXIC, GENOTOXIC, AND ENDOCRINE DISRUPTION ACTIVITY OF WASTEWATER TREATMENT PLANTS.
- Authors
ISIDORI, MARINA; LAVORGNA, MARGHERITA; PALUMBO, MARIA; PICCIOLI, VERONICA; PARRELLA, ALFREDO
- Abstract
Toxicity and endocrine interference of influent and effluent waters from domestic and industrial wastewater treatment plants were determined. In addition, chemical analyses were performed to detect the presence of 17β-estradiol, 17α-ethinyl estradiol, nonylphenol, 4-octylphenol, and p-t-octylphenol as well as lead, copper, and cadmium in these matrices. The results showed that despite low acute toxic potential, most of the samples tested showed both genotoxicity and endocrine interference. Furthermore, to establish whether the observed effects were caused by the alkylphenols and the heavy metals detected, toxic, genotoxic, and endocrine interference tests also were performed on pure chemicals. The acute toxicity was measured on the crustacean Daphnia magna. The estrogenic activity was determined by using the yeast estrogen screen with Saccharomyces cerevisiae RMY326, whereas the SOS Chromotest and Ames test detected the genotoxicity on Escherichia coli PQ37 and Salmonella typhimurium TA98 and TA100, respectively. The results showed that the toxicity found in the matrices did not match the values found for pure chemicals, but a clear correlation was found between alkylphenols and genotoxicity. Both heavy metals and alkylphenols took part in the endocrine interference activity.
- Subjects
PHYSIOLOGICAL effects of phenols; PHENOLS &; the environment; GENETIC toxicology; ENDOCRINE disruptors; SEWAGE disposal plants &; the environment; ESTRADIOL; NONYLPHENOL &; the environment; ENVIRONMENTAL toxicology research
- Publication
Environmental Toxicology & Chemistry, 2007, Vol 26, Issue 8, p1686
- ISSN
0730-7268
- Publication type
Article
- DOI
10.1897/06-320R2.1