This article reports on the move of Illumina of San Diego, California, to offer a whole-genome sequencing service for under 50,000 U.S. dollars in 2009. The Personal Genome Sequencing Service uses the Genome Analyzer system of the company. The service will provide data on patients' entire genome sequence including information on single nucleotide polymorphisms (SNP) variations, insertions, deletions and rearrangements.