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- Title
Profile of a bacterial tumor killer.
- Authors
Forbes, Neil S.
- Abstract
The article discusses the microbial genomics of a non toxic bacteria, clostridium noviy-NT, for the treatment of cancer. The article probes Clostridium novyi spores containing mRNA and producing lipases, enumerating a set of criteria for cancer therapy by bacteria. The article states factulative and obligate anaerobes targeting mechanism on metastasis and large tumors, suggesting in favor combined usage of bacterial and traditional drugs for the effective treatment of cancer.
- Subjects
CANCER treatment; THERAPEUTIC use of bacteria; MICROBIAL genomics; CLOSTRIDIUM novyi; METASTASIS; MESSENGER RNA; GENOMIC imprinting
- Publication
Nature Biotechnology, 2006, Vol 24, Issue 12, p1484
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt1206-1484