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- Title
The impact of worst pattern of invasion on the extension of surgical margins in oral squamous cell carcinoma.
- Authors
Köhler, Hugo Fontan; Vartanian, José Guilherme; Pinto, Clóvis Antônio Lopes; da Silva Rodrigues, Ivete Fabelo Pereira; Kowalski, Luiz Paulo
- Abstract
Background: To evaluate margins for oral carcinoma according to types of invasion front. Methods: Retrospective cohort of 772 patients with worst pattern of invasion (WPOI) graded 1–5. Local recurrence was the outcome of interest. Results: Local recurrences occurred in 164 patients (21.2%) and was affected by WPOI type 4/5, margin distance, perineural invasion, and adjuvant radiotherapy. In patients with WPOI types 1/2/3, a cutoff of 1.7 mm was considered ideal margin extent and in patients with WPOI types 4/5, the cutoff was 7.8 mm. Patients below these thresholds had a significantly higher incidence of local recurrence. Conclusions: Different WPOI determine the ideal extent of surgical margins as 1.7 mm for patients with types 1–3, and 7.8 mm in patients with types 4/5.
- Subjects
SURGICAL margin; SQUAMOUS cell carcinoma
- Publication
Head & Neck, 2022, Vol 44, Issue 3, p691
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.26956