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- Title
The Translational Value of Rodent Models of Sepsis.
- Authors
Matthay, Michael A.; Schmidt, Eric P.; Bastarache, Julie A.; Calfee, Carolyn S.; Frevert, Charles W.; Martin, Thomas R.
- Abstract
The article informs about the value of rodent models in understanding and treating sepsis, addressing both their significance and limitations in translational research. Topics include the similarities in biological responses between rodents and humans, the contribution of rodent models to significant therapeutic advancements in sepsis treatment, and efforts to improve the relevance of rodent models to human sepsis through incorporating clinical comorbidities and treatments.
- Subjects
SEPSIS; RODENTS; RESPIRATORY distress syndrome
- Publication
American Journal of Respiratory & Critical Care Medicine, 2024, Vol 209, Issue 5, p488
- ISSN
1073-449X
- Publication type
Article
- DOI
10.1164/rccm.202308-1489VP