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- Title
Inflammatory myofibroblastic tumor of the oral cavity: A case report and literature review.
- Authors
Shetty, Subraj; Pereira, Treville; Desai, Rajiv; Shetty, Subraj J; Desai, Rajiv S
- Abstract
Inflammatory myofibroblastic tumor (IMT) is a rare tumor of unknown etiology and pathogenesis. The lesion has been recognized to occur at various sites but rarely affects the head and neck region. A 29-year-old male presented with a 13 months' history of a slow growing, painless growth in maxillary left posterior gingiva. An excisional biopsy was performed under local anesthesia. Microscopic examination revealed a compact cellular spindle cell proliferation with collagenous stroma having storiform architecture. Immunohistochemistry revealed that the tumor cells were positive for smooth muscle actin, CD-68 and negative for anaplastic lymphoma kinase. Oral IMT should be included in the differential diagnosis of localized gingival enlargement mimicking oral hyperplastic/reactive lesions.
- Subjects
ANAPLASTIC lymphoma kinase; LITERATURE reviews; GINGIVAL hyperplasia; SMOOTH muscle; LOCAL anesthesia; TUMORS
- Publication
Journal of Cancer Research & Therapeutics, 2019, Vol 15, Issue 3, p725
- ISSN
0973-1482
- Publication type
case study
- DOI
10.4103/jcrt.JCRT_1044_16