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- Title
Thrombotic microangiopathy with liver, gut, and bone infarction (catastrophic antiphospholipid syndrome) associated with HELLP syndrome.
- Authors
Koenig, Martial; Roy, Michel; Baccot, Sylviane; Cuilleron, Muriel; de Filippis, Jean-Pierre; Cathébras, Pascal
- Abstract
Hemolysis, elevated liver enzymes, low platelet count (HELLP) syndrome is a thrombotic microangiopathy complicating pregnancy and shares many clinical and biological features with thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). Thrombotic microangiopathy is also a pathological feature of catastrophic antiphospholipid syndrome (CAPS). An association between refractory HELLP syndrome and antiphospholipid syndrome (APS) has been reported in a few cases. We describe a 19-year-old woman with APS and multiorgan failure conforming to a diagnosis of CAPS who developed refractory HELLP syndrome.
- Subjects
THROMBOTIC microangiopathies; BONE infarction; INFARCTION; CATASTROPHIC illness; ANTIPHOSPHOLIPID syndrome; AUTOIMMUNE diseases
- Publication
Clinical Rheumatology, 2005, Vol 24, Issue 2, p166
- ISSN
0770-3198
- Publication type
Article
- DOI
10.1007/s10067-004-1017-1