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- Title
Predicting PTSD Prospectively Based on Prior Trauma History and Immediate Biological Responses.
- Authors
DELAHANTY, DOUGLAS L.; NUGENT, NICOLE R.
- Abstract
Studies examining the biopsychology of posttraumatic stress disorder (PTSD) have suggested that PTSD is characterized by alterations of the primary stress pathways: the hypothalamic-pituitary-adrenal (HPA) axis and the sympathetic nervous system (SNS). More recent investigations point to the presence of these alterations soon after a traumatic event, leading researchers to suggest that acute biological responses may serve as risk or resilience factors for the development of PTSD. The present article reviews the evidence for early biological predictors of PTSD, with a focus on the role of prior trauma as a contributor to both hormonal abnormalities and increased risk for the development of PTSD following a subsequent trauma.
- Subjects
POST-traumatic stress disorder; SYMPATHETIC nervous system; HYPOTHALAMIC-pituitary-adrenal axis; PSYCHOBIOLOGY; PSYCHOLOGICAL resilience
- Publication
Annals of the New York Academy of Sciences, 2006, Vol 1071, Issue 1, p27
- ISSN
0077-8923
- Publication type
Article
- DOI
10.1196/annals.1364.003