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- Title
Synthesis and Biological Activity of Unsymmetrical Monoterpenylhetaryl Disulfides.
- Authors
Sudarikov, Denis V.; Gyrdymova, Yulia V.; Borisov, Alexander V.; Lukiyanova, Julia M.; Rumyantcev, Roman V.; Shevchenko, Oksana G.; Baidamshina, Diana R.; Zakarova, Nargiza D.; Kayumov, Airat R.; Sinegubova, Ekaterina O.; Volobueva, Alexandrina S.; Zarubaev, Vladimir V.; Rubtsova, Svetlana A.
- Abstract
New unsymmetrical monoterpenylhetaryl disulfides based on heterocyclic disulfides and monoterpene thiols were synthesized for the first time in 48–88% yields. Hydrolysis of disulfides with fragments of methyl esters of 2-mercaptonicotinic acid was carried out in 73–95% yields. The obtained compounds were evaluated for antioxidant, antibacterial, antifungal activity, cytotoxicity and mutagenicity.
- Subjects
BIOSYNTHESIS; METHYL formate; DISULFIDES; MONOTERPENES
- Publication
Molecules, 2022, Vol 27, Issue 16, p5101
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules27165101