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- Title
Characteristics and prognosis of borderline ovarian tumors in pre and postmenopausal patients.
- Authors
Tal, Ori; Ganer Herman, Hadas; Gluck, Ohad; Levy, Tally; Kerner, Ram; Bar, Jacob; Sagiv, Ron
- Abstract
<bold>Objective: </bold>To compare patient characteristics, imaging results, surgical management and prognosis of borderline ovarian tumors (BOT) between pre and postmenopausal patients.<bold>Materials and Methods: </bold>A retrospective cohort of all cases of histologically verified BOT between 1990-2018, comparing presentation, imaging, surgical procedures and recurrence. Patients were included in the postmenopausal group if they reported 12 months of amenorrhea with or without menopausal symptoms.<bold>Results: </bold>During this 28 year study period, 66 operations were performed in which BOT was confirmed. Postmenopausal patients were 37-89 years old and premenopausal patients 18-50 years old, with an average age of 63.9 ± 13.4 and 36.2 ± 8.4 years, respectively (p < 0.001). The majority of patients in both groups were diagnosed due to abdominal pain, followed by incidental diagnosis on routine ultrasound. Imaging and CA-125 levels upon presentation were similar. Almost sixty percent of postmenopausal and 26.3% of premenopausal patients underwent laparotomy (p = 0.01), while those who underwent laparoscopy were 35.7% and 60.5%, respectively (p = 0.03). Most postmenopausal patients underwent bilateral salpingo-oophorectomy (BSO), whereas premenopausal surgeries involved cystectomy. Nearly all study patients were diagnosed in stage one. Malignant transformation occurred in 7.1% of postmenopausal patients. No malignant transformation was found in premenopausal patients.<bold>Conclusion: </bold>BOT's present similarly in pre and postmenopausal patients. Postmenopausal patients undergo more extensive surgery, and are diagnosed in early stage disease. Despite a tendency for a more conservative approach in premenopausal patients, prognosis is similar in both groups.
- Subjects
OVARIAN cancer; OPERATIVE surgery; OLDER patients; HYSTERO-oophorectomy; PROGNOSIS; AMENORRHEA; PERIMENOPAUSE; OVARIAN tumors; RETROSPECTIVE studies; POSTMENOPAUSE
- Publication
Archives of Gynecology & Obstetrics, 2020, Vol 302, Issue 3, p693
- ISSN
0932-0067
- Publication type
journal article
- DOI
10.1007/s00404-020-05652-w